Protein Alignment Ir76b and glr-8

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001368711.1
• Gene: glr-8 / 180924
• WormBaseID: WBGene00001619
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 519
• Identity: 110/519 - (21%)
• Similarity: 194/519 - (37%)
• Gaps: 100/519 - (19%)

  Fly    27 NLIQ-MGENGTLSPVTELPMDVDASEAGFDADAPVETLETINRKKPKLREMLDWIGGKHLR--IA 88
            |::: :.|.....|.|.|..|.        .||  .||.  |.|...|.||    .|:.|:  :.
 Worm    21 NILESINEKVAHPPQTSLTSDY--------GDA--YTLS--NEKHFSLSEM----KGRTLKMVVP 69

  Fly    89 TLEDFPLSYTE-----VLENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSDFDRSLI 148
            .:|...::|..     |.:.|  .|.||..:|:..:.|:.|.|||::....:..|
 Worm    70 AIEPPYVNYVNFSDAAVTDKG--YGPGVVMEILKEIGKRLNLTYEILPALGSTWG---------- 122

  Fly   149 EMVNSS-----------TVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLL 202
            |.:|.|           .|||.|.  .::.:....|....|...:.|...:|.|..|......||
 Worm   123 EYLNGSWTGAFGQLVRGEVDLLAG--GAIMEYDRSVIADLTYPFQFEPTGIMIRSPEKYEDDTLL 185

  Fly   203 ---APFEFWVWILILVSLLAVGPIIYALIILRNRLTGDGQQTPYSLGHCAWFVYGALMKQGSTLS 264
               .||.:.||::....:|..|.|...:..:..::..:...||:   ...|..:...::||....
 Worm   186 IVTEPFSWEVWVITAAVILISGVIFLVMTNIIRKVYEEMTVTPF---ESIWVFFSIFVQQGLPEQ 247

  Fly   265 PIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNKHFVSMRGGGVEYA 329
            |.:.|.|:|.|.||:....|::.:|.:|.|...:.|..:|:..::.::...|     :|   ::.
 Worm   248 PRSWSCRVLVALWWLASITLSATFTGSLVALFAVDKTNVPFQNIDQLVRLVK-----QG---KFE 304

  Fly   330 IRTTNESLSMLNRMIQNNYAVFSDETNDTYNLQNYVEK------NGYVFVRDRP---------AI 379
            |.....|.:....:.::...|:.|..::.  :.|:..|      .|..|||..|         .:
 Worm   305 IVMDENSFTRTEMIARSKLPVYRDLWHEM--IVNHKVKYVNGIARGVAFVRANPGYALLGPMATL 367

  Fly   380 NIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESG--- 441
            |...|.|.   |.:.|:|..:....::   |.:|         .|..|..|..::..:||.|
 Worm   368 NFYAYSDC---KVILFNDGILPVYLSI---PLVK---------NSIYSPYFSTKIREMVERGFTQ 417

  Fly   442 --IVKHLSKRNLPSAEICPQDLGGTERQLRNGDLMMTYYIMLAGFATALAVFSTELMFRYVNSR 503
              |..:.|...:.....|.....|.:..|........:::.|.|....||:|..|.:|::...:
 Worm   418 KWIADYRSYVAMQKINECNSTTIGPKSYLDLKRAQGAFWVFLGGAGLGLALFVGEFIFKFFREK 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	26/126 (21%)
		Lig_chan	209..458	CDD:459656	52/268 (19%)
glr-8	NP_001368711.1	PBP2_iGluR_ligand_binding	62..424	CDD:270219	83/403 (21%)