Protein Alignment Ir76b and glr-5

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_505244.1
• Gene: glr-5 / 179251
• WormBaseID: WBGene00001616
• Length: 932
• Species: Caenorhabditis elegans
• Alignment Length: 494
• Identity: 104/494 - (21%)
• Similarity: 170/494 - (34%)
• Gaps: 156/494 - (31%)

  Fly    19 PLNDSPPTNLIQMGENGTLSPV--TELPMDVDASEAGFDADAPVE-TLETINRKKPKLREMLDWI 80
            ||..:....:..:|.:|.|..:  .|...:|..:.:| |:.|.:: .::..:..||
 Worm   383 PLKSNFSMRIQLLGYSGRLDDIGFWEPATNVHVNMSG-DSKAQLQRNVQVSDELKP--------- 437

  Fly    81 GGKHLRIATLEDFPLSYTEVLENGTRVGHGVSFQ--IIDF---LKKKFNFTYEVVVPQDNIIGSP 140
               |.|:.|:.:.|  |..:.:|...:.....|:  .||.   |.|...|||.:...:|...|:.
 Worm   438 ---HFRVTTIMERP--YVMLKKNHYELDANSKFEGFCIDLLAELSKDLGFTYTIHAVKDGKYGND 497

  Fly   141 ----SDFDRSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGL 201
                ..:|..:.|::... .::|.|.:.....:...|.::...|..|..|:......:.......
 Worm   498 KYGNGSWDGMMGEILRGE-AEMAVAPLTVNYRRSEAVDFTKPFLSLGISILYKVPDDQQPDLFSF 561

  Fly   202 LAPFEFWVWILILVSLLAVGPIIY---------------------------------ALIILRNR 233
            |.|..:.:|..|..|::.|...:|                                 |.|::.|.
 Worm   562 LNPLSWQIWTAIATSIITVTLGMYFVANVTPYEWNLNFSCCTAHEPHPAAAFATNQEAPIVMSNN 626

  Fly   234 LTGDGQQTPYSLGHCAWFVYGALMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTL 298
                     ||..:..|:|...::|.|....|.|.|||||..|||:|..::.|.|||||.|.||:
 Worm   627 ---------YSFWNTVWYVLSTMLKGGCDFGPRAVSTRLLGGTWWVFYLVIISAYTANLAAVLTV 682

  Fly   299 SKFTLPYNTVNDILT---------------------------------KNKH-FVSMRGGGVEYA 329
            |:..:|...::|:..                                 |:|. ||:..|.|||.|
 Worm   683 SRPYIPIKNLDDLANQTTISYGTIRGGSTMQFFQESRIAAHVKMWQYMKDKDVFVTSNGKGVERA 747

  Fly   330 IRTTNESLSMLNRMIQNNYAVFSDETNDTYNLQ---------NYVEKNGYVFV-------RDRPA 378
                   |||       |||...:.|:..|..|         ..:...||...       .||.:
 Worm   748 -------LSM-------NYAYLMESTSLEYETQQNCNLTQIGGVLGSKGYGIALAKKSEWTDRIS 798

  Fly   379 INIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRT 417
            ..|:||                      ||...::.|:|
 Worm   799 RQILLY----------------------AKRGIIEMKKT 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	24/117 (21%)
		Lig_chan	209..458	CDD:459656	66/292 (23%)
glr-5	NP_505244.1	PBP1_iGluR_non_NMDA-like	26..417	CDD:380591	7/33 (21%)
		PBP2_iGluR_Kainate	438..819	CDD:270432	92/426 (22%)
		Lig_chan	566..854	CDD:459656	66/295 (22%)