Protein Alignment Ir76b and glr-1

DIOPT Version :9

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_498887.2
• Gene: glr-1 / 176204
• WormBaseID: WBGene00001612
• Length: 962
• Species: Caenorhabditis elegans
• Alignment Length: 620
• Identity: 139/620 - (22%)
• Similarity: 219/620 - (35%)
• Gaps: 130/620 - (20%)

  Fly    15 VACPPLND-SPPTNLIQMGENGTLSPVTELPMDVDASEA---------------GFD---ADAPV 60
            :.|.||:| |.|.......|:|....|....|.:...|.               .||   .|...
 Worm   354 IYCDPLSDRSHPNRPFSSFEHGKTIGVAFRNMKIGHKEGTLTGNIEFDRFGNRKNFDVSIVDLVS 418

  Fly    61 ETLETINRKKPKLREMLDWIGG----------KHLR------------IAT--LEDFPLSYTEVL 101
            .|..|.|.|     |:|.|..|          :|.|            :.|  :..|.:...|.|
 Worm   419 NTKATFNSK-----EVLAWRQGVGFFSNRTVAQHSRKSQNDHKDNQVIVLTNLVAPFVMIKRECL 478

  Fly   102 E-------NGTRVGHGVSFQIIDFLKKKF-NFTYEVVVPQDNIIGSPSDFDRSLIEMVNSSTVDL 158
            |       .|.....|....::..|..|. .|.||:.:  ....|| ...|.|...|:.......
 Worm   479 EMANLTECQGNNKFEGFCIDLLKLLADKIEEFNYEIKL--GTKAGS-KQADGSWDGMIGELLSGR 540

  Fly   159 AAAFIPSLS---DQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWVWILILVSLLAV 220
            |.|.:.||:   ::...|.:|...:..|..||:.:..::..|....:.|....:|:.|:.:.:.|
 Worm   541 AHAVVASLTINQERERVVDFSKPFMTTGISIMIKKPDKQEFSVFSFMQPLSTEIWMYIIFAYIGV 605

  Fly   221 GPIIYALIIL-----RNRLTGDGQQT---PYSLGHCAWFVYGALMKQGSTLSPIADSTRLLFATW 277
            ..:|:.:...     |...|..|..|   .:|:.:|.||...|.|:||:.:.|.:.|.|:..:.|
 Worm   606 SVVIFLVSRFSPYEWRVEETSRGGFTISNDFSVYNCLWFTLAAFMQQGTDILPRSISGRIASSAW 670

  Fly   278 WIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNKHFVSMRGGG-----VEYAIRTTNESL 337
            |.|..|:.|.|||||.|||||.|...|..:|.|:..::|....::|||     .:|:      |:
 Worm   671 WFFTMIIVSSYTANLAAFLTLEKMQAPIESVEDLAKQSKIKYGIQGGGSTASFFKYS------SV 729

  Fly   338 SMLNRMIQNNYAVFSDETNDTYNLQNYVE--------KNGYVFVRDRPAINIMLYRDYLYRKTVS 394
            .:..||    :.....:....: :.:|.|        |..|.|:.:..|              ..
 Worm   730 QIYQRM----WRYMESQVPPVF-VASYAEGIERVRSHKGRYAFLLEATA--------------NE 775

  Fly   395 FSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKRNLPSAEICPQ 459
            :.:.:..|................|.|.||:.....:..:|.|.|.|.:|.|..:.......|
 Worm   776 YENTRKPCDTMKVGANLNSIGYGIATPFGSDWKDHINLAILALQERGELKKLENKWWYDRGQC-- 838

  Fly   460 DLG----GTERQLRNGDLMMTYYIMLAGFATALAVFSTELMFRYVNSRQEANKWARHGIGRTPNG 520
            |.|    |:...|....:...:||::.|...::.....|.::|   ||.||.|         .|.
 Worm   839 DAGITVDGSSASLNLSKVAGIFYILMGGMVISMLAALGEFLYR---SRIEARK---------SNS 891

  Fly   521 QSVAPSRWLRGWRRLNSGHGQLLGASTHGQNVTPP 555
            .|:..:    ..:.|.|.....|..|..|..|..|
 Worm   892 NSMVAN----FAKNLKSALSSQLRLSVEGGAVAQP 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	88/399 (22%)
glr-1	NP_498887.2	PBP1_iGluR_AMPA	10..439	CDD:107375	22/89 (25%)
		ANF_receptor	44..417	CDD:279440	14/62 (23%)
		Periplasmic_Binding_Protein_Type_2	457..832	CDD:304360	91/402 (23%)
		Lig_chan	593..867	CDD:278489	70/300 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910