Protein Alignment Ir76b and glr-4

DIOPT Version :9

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001254126.1
• Gene: glr-4 / 174258
• WormBaseID: WBGene00001615
• Length: 951
• Species: Caenorhabditis elegans
• Alignment Length: 615
• Identity: 134/615 - (21%)
• Similarity: 222/615 - (36%)
• Gaps: 147/615 - (23%)

  Fly    54 FDADAPVETLETINRKKPKLREMLDWIGGKHLRIATLEDFPLSYTEVLENGTRVGHGVSFQIIDF 118
            ||.|...|.||                 |.|||:....:.|.    |::.|.....|....:::.
 Worm   396 FDIDPDSEDLE-----------------GLHLRVVVYLEEPF----VIKTGENQYEGFCIDLLNE 439

  Fly   119 LKKKFNFTYEVVVPQDNIIGSPSDFDR--SLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLD 181
            :.:...|.|.::..||...|...:..|  .:|..:.....||:.:.:.....:...|.::...:.
 Worm   440 MTQVLKFNYTIIEVQDGTYGIEDESGRWNGIIGALQRHEADLSLSAVTITYSRAEVVDFTLPFMH 504

  Fly   182 EGEWIMVMQRPRESASGS--GLLAPFEFWVWILILVSLLAVGPIIYALIIL-------------- 230
            .|..|::.:...|:..||  ..|.|....|||.:|:|...|.   |::.||
 Worm   505 LGISILLARTSEETDKGSLWTFLEPLSLTVWISLLISYCIVS---YSMHILAKFSPYEWYNLERI 566

  Fly   231 --RNRLTGDGQQTPYSLGHCAWFVYGALMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANLT 293
              |:......|:..:::.:..||..|:||:|||.:.|.|.:|||:...||:|..|:.|.|||.|.
 Worm   567 DERDFENIKNQKNQFTVLNSFWFTMGSLMQQGSDVIPRAAATRLIAVVWWMFTQIIISSYTAQLA 631

  Fly   294 AFLTLSKFTLPYNTVNDILTKNKHFVSMRGGGVEYAIRTTNESLSMLNR----MIQNNYAVFSDE 354
            ||||:.:.:.|..:..|:..:.|         :.|.:..:..::.....    |.:..::|....
 Worm   632 AFLTVERMSTPIESTQDLANQQK---------IRYGVLKSGSTMDFFRESKIPMYERMWSVMESS 687

  Fly   355 T-----NDTYNLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKK 414
            :     |.:......|:..||.::.:...:...|.||...:......|.|.:
 Worm   688 SPGVFVNSSREGIARVKSGGYAYMMESSMLEYYLERDCELQSIGGLLDSKGY------------- 739

  Fly   415 KRTFAYPIGSNLSQLFDPELLHLVESGIVKHL------SKRNLPSAEICPQDLGGTERQLRNGDL 473
              ..|.|.||.|..:....:|.|.|..|::.|      .:|..||....|.: ..|..:.:|  :
 Worm   740 --GIALPKGSPLRDILSRTVLQLQERTILEALKNKWWRDRREGPSCGPPPSE-KATNSKPQN--I 799

  Fly   474 MMTYYIMLAGFATALAVFSTELMFRYVNSRQEANKWARHGIGRTPNGQSVAPSRWLRGWRRLNSG 538
            ...:|::|.|...|..:...|..   :.||.||.:.....:|:..:        |.||    ||.
 Worm   800 FGIFYVLLTGLIVAFLLACGEYC---IESRHEAFRLKLTIVGKFMD--------WYRG----NSN 849

  Fly   539 H---------------GQLLGASTHGQNVTPP---------PPYQSIFNGG--------SHGDPL 571
            .               ||.:..||.....|||         |...||.:..        ..|.|:
 Worm   850 DSKQRSKLRNMQLDTAGQEVSISTRHDPPTPPQPALTSRPDPTRLSISSPAPTICVVSCDDGTPI 914

  Fly   572 NRWRRPLANGNALGNGVLLGGDSEGGVRRL 601
            :|.|.|              ..|..|:|||
 Worm   915 SRDRPP--------------SISRAGLRRL 930

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	82/382 (21%)
glr-4	NP_001254126.1	PBP1_iGluR_Kainate	30..385	CDD:107377
		ANF_receptor	45..365	CDD:279440
		Periplasmic_Binding_Protein_Type_2	410..775	CDD:304360	85/395 (22%)
		Lig_chan	533..810	CDD:278489	70/306 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010