Protein Alignment Ir76b and nmr-1

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_495033.2
• Gene: nmr-1 / 173929
• WormBaseID: WBGene00003774
• Length: 1025
• Species: Caenorhabditis elegans
• Alignment Length: 570
• Identity: 121/570 - (21%)
• Similarity: 191/570 - (33%)
• Gaps: 165/570 - (28%)

  Fly    75 EMLDWIGG---------KHLRIATLEDFPLSYTE------------------------------- 99
            :.::|.||         ||||:.|:.|.|..||.
 Worm   378 DSIEWAGGTKPLEISLPKHLRVVTVADPPFVYTTPIGSPSQCAELGNTVVEWSIFDKIVVSGPWY 442

  Fly   100 ----VLENGTR--VGHGVSFQIIDFLK---------KKFNF------TYEVV-------VPQDNI 136
                .|||.|.  ...|::..::..|.         ..|.|      :|.||       :....:
 Worm   443 SCPLTLENSTEYFCCAGLAIDLLSNLSLPEANNSIDTSFTFSLHLNESYGVVQASETTGITISGV 507

  Fly   137 IGSPSDFDRSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGL 201
            ||.           ::..|.|:|...|....::...|.::...|..|..|:....||:|...| .
 Worm   508 IGE-----------LDGDTADMAIGGITINPERERIVDFTEPWLYHGIRILEKNIPRDSPMQS-F 560

  Fly   202 LAPFEFWVWILILVSLLAVGPIIYALII-----------------LRNRL---TGDGQQTPYSLG 246
            |.|.:..:|..:.:|::.||..||.|..                 |:...   .|.......:.|
 Worm   561 LQPLQSSLWTALFISVILVGLAIYCLDFKSPFERFYQADKEMEQDLKKEFELWIGKDADENVNFG 625

  Fly   247 HCAWFVYGALMKQG-STLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVND 310
            ...|||:|.|:..| |..:|.:.|.|:|...|..|..|:.:.|||||.|||.|.:.......|.|
 Worm   626 EAMWFVWGVLLNSGVSEKTPRSCSARVLGIVWCGFCMIMVASYTANLAAFLVLDQPEKGLTGVTD 690

  Fly   311 ILTKNK----HFVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSDETNDTYNLQNYVEKNGYV 371
            ...:|.    .|.::....|....:...|..||..:|..:|....|:..:...        ||.:
 Worm   691 PRLRNPSANFSFGTVLNSNVYQYFKRHVELSSMFRKMEPHNVRRASEAVHSLL--------NGSL 747

  Fly   372 --FVRDRPAINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPE- 433
              |:.|...:.....|               ||........|.:.    ||.||...:..:.|.
 Worm   748 DAFIWDSTRLEFEAAR---------------HCELRTRGSLFGRS----AYGIGLQKNSPWTPHI 793

  Fly   434 ---LLHLVESGIVKHLSKRNLPSAEICPQDLGGT-------ERQLRNGDLMMTYYIMLAGFATAL 488
               :|.:.|||:::.|.::.:        |.||.       :...|.|.:.|....:|.....||
 Worm   794 TSAILRMSESGVMEKLDQKWI--------DRGGPNCVVEAHKSPARLGLVNMKDIFILVSSGVAL 850

  Fly   489 AVFSTELMFRYVNSRQEANKWARHGIGRTPNGQSVAPSRWLRGWRRLNSG 538
            .:|.:.:...|  .|:.|:|..|..|          .:|:.:.|..|..|
 Worm   851 GIFLSFVEVSY--GRRLADKGRRRRI----------VTRYFQKWHDLTLG 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	30/167 (18%)
		Lig_chan	209..458	CDD:459656	62/279 (22%)
nmr-1	NP_495033.2	Periplasmic_Binding_Protein_type1	19..384	CDD:471960	1/5 (20%)
		PBP2_iGluR_NMDA_Nr1	394..822	CDD:270437	101/474 (21%)
		Lig_chan	566..844	CDD:459656	68/312 (22%)
		LITAF	949..1017	CDD:197841