Protein Alignment Ir76b and gria3a

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_073805840.1
• Gene: gria3a / 170452
• ZFINID: ZDB-GENE-020125-5
• Length: 940
• Species: Danio rerio
• Alignment Length: 555
• Identity: 117/555 - (21%)
• Similarity: 203/555 - (36%)
• Gaps: 141/555 - (25%)

  Fly    87 IATLEDFPL-----SYTEVLENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSDFDRS 146
            :.|:.:.|.     :|.: ||...|. .|....:...:.|.....|::.:..|...|:.....::
Zfish   420 VTTIMEAPYVMYKRNYMQ-LEGNDRY-EGYCVDLASEIAKHVGIKYKLSIVADGKYGARDPETKT 482

  Fly   147 LIEMVNS---STVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASG-SGLLAPFEF 207
            ...||..   ...|:|.|.:.....:...:.:|...:..|..||: ::|::|..| ...|.|..:
Zfish   483 WNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMI-KKPQKSKPGVFSFLDPLAY 546

  Fly   208 WVWILILVSLLAVGPIIYALIILR----------NRLTGDGQQTP-----YSLGHCAWFVYGALM 257
            .:|:.|:.:.:.|..:::  ::.|          |..|.|.|..|     :.:.:..||..||.|
Zfish   547 EIWMCIVFAYIGVSVVLF--LVSRFSPYEWHLDDNEETKDPQTPPDPPNDFGIFNSLWFSLGAFM 609

  Fly   258 KQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLP--------------YNTV 308
            :||..:||.:.|.|::...||.|..|:.|.|||||.||||:.:...|              |.|:
Zfish   610 QQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTL 674

  Fly   309 NDILTK-----------NKHFVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSDETN------ 356
            :...||           .|.:..|:.......::||.:.::.: |..:..:|...:.|.
Zfish   675 DSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFVKTTPDGVARV-RKSKGKFAFLLESTMNEYIEQ 738

  Fly   357 ----DTYNLQNYVEKNGYVFVRD-----RPAINIMLYR-------DYLYRK----------TVSF 395
                ||..:...::..||.....     |.|:|:.:.:       |.|..|          ....
Zfish   739 RKPCDTMKVGGNLDSKGYGVATPKGSALRSAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGD 803

  Fly   396 SDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHL-SKRNLPSAEICPQ 459
            |..|..||....   :|...||   |:  ||:      :|.|.|.||:..| :|......|...:
Zfish   804 SKHKARCPTVSL---WLTDIRT---PV--NLA------VLKLSEQGILDKLKNKWWYDKGECGTK 854

  Fly   460 DLGGTER--QLRNGDLMMTYYIMLAGFATALAVFSTELMFRYVNSRQEANKWARHGIGRTPNGQS 522
            |.|..::  .|...::...:||::.|...|:.|...|..::   |.||..:
Zfish   855 DSGSKDKTSALSLSNVAGVFYILVGGLGLAMTVALVEFCYK---SHQETKR-------------- 902

  Fly   523 VAPSRWLRGWRRLNSGHGQLLGASTHGQNVTPPPP 557
                                |..:.:.||..|.||
Zfish   903 --------------------LKLAKNAQNFKPAPP 917

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	20/112 (18%)
		Lig_chan	209..458	CDD:459656	74/321 (23%)
gria3a	XP_073805840.1	None