Protein Alignment Ir76b and Grin2d

DIOPT Version :9

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_036008580.1
• Gene: Grin2d / 14814
• MGIID: 95823
• Length: 1345
• Species: Mus musculus
• Alignment Length: 613
• Identity: 129/613 - (21%)
• Similarity: 223/613 - (36%)
• Gaps: 173/613 - (28%)

  Fly    83 KHLRIATLEDFPLSYTEVLE--NGTRVGHGVSFQ------------------------------I 115
            :||.:||||:.|....|..:  :||.:...|..:                              .
Mouse   432 QHLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSLVAPRSPPPDAPRPEKRCCKGFC 496

  Fly   116 IDFLKK---KFNFTYEVVVPQDNIIGSPSD-FDRSLIEMVNSSTVDLAAAFIPSLSDQRS-FVYY 175
            ||.||:   ...|:|::.:..:...|...| ....:|..|.....|:|...: :::::|| .|.:
Mouse   497 IDILKRLAHTIGFSYDLYLVTNGKHGKKIDGVWNGMIGEVFYQRADMAIGSL-TINEERSEIVDF 560

  Fly   176 STTTLDEGEWIMVMQRPRESASGSGLLA-----------PFEFWVWILILVSLLAV--------- 220
            |...::.|..:|| .|...:.|.|..||           |:...||:::.|..|.|
Mouse   561 SVPFVETGISVMV-ARSNGTVSPSAFLAFAWLMPPMSPEPYSPAVWVMMFVMCLTVVAVTVFIFE 624

  Fly   221 --GPIIYALIILRNRLTGDGQQ---TPYSLGHCAWFVYGALMKQGSTL-SPIADSTRLLFATWWI 279
              .|:.|      ||....|::   :.:::|...|.::..:......: :|...:::::...|..
Mouse   625 YLSPVGY------NRSLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAF 683

  Fly   280 FITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKN----------KHFVSMRGGGVEYAIRTTN 334
            |..|..:.|||||.||:...::.   :||:.:..:.          ..|.::..|..|..||:
Mouse   684 FAVIFLASYTANLAAFMIQEEYV---DTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRS-- 743

  Fly   335 ESLSMLNRMIQNNYAVFSDETNDTYNLQNYVE------KNGYV--FVRDRPAINIMLYRDYLYRK 391
                  |....::|.|       .|| |..||      |.|.:  |:.|...:|.|..:|. ..|
Mouse   744 ------NYPDMHSYMV-------RYN-QPRVEEALTQLKAGKLDAFIYDAAVLNYMARKDE-GCK 793

  Fly   392 TVSFSDEKVHCP--FAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVE----SGIVKHLSKRN 450
            .|:....||...  :.:|    |.|...:..||...|.|....:.:.::|    |||. |..|..
Mouse   794 LVTIGSGKVFATTGYGIA----LHKGSRWKRPIDLALLQFLGDDEIEMLERLWLSGIC-HNDKIE 853

  Fly   451 LPSAEICPQDLGGTERQLRNGDLMMTYYIMLAGFATALAVFSTE-LMFRYVNSRQEANKW-ARHG 513
            :.|:::...::.|            .:|::|.....:|.||:.| |::           | .||.
Mouse   854 VMSSKLDIDNMAG------------VFYMLLVAMGLSLLVFAWEHLVY-----------WRLRHC 895

  Fly   514 IGRTPNGQSVAPSRWLRGWRRLNSGHGQLLGASTHGQNVTPPPPYQSIFN----------GGSHG 568
            :|         |:..:......:.|......|........||||.|.:.:          |.:..
Mouse   896 LG---------PTHRMDFLLAFSRGMYSCCSAEAAPPPAKPPPPPQPLPSPAYPAARPPPGPAPF 951

  Fly   569 DP-----LNRWRRPLA----NGNALGNG 587
            .|     .:||||...    .|.||.:|
Mouse   952 VPRERAAADRWRRAKGTGPPGGAALADG 979

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	92/436 (21%)
Grin2d	XP_036008580.1	Periplasmic_Binding_Protein_type1	<156..415	CDD:415822
		PBP2_iGluR_NMDA_Nr2	432..849	CDD:270436	96/449 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846425
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740