Protein Alignment Ir76b and Grik2

DIOPT Version :9

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_011241422.1
• Gene: Grik2 / 14806
• MGIID: 95815
• Length: 943
• Species: Mus musculus
• Alignment Length: 543
• Identity: 114/543 - (20%)
• Similarity: 199/543 - (36%)
• Gaps: 120/543 - (22%)

  Fly    41 TELPMDV-DASEAGFDADA---PVETLETINRKKPKLREMLDWIGGKHLRIATL----------E 91
            |:..:|| ...|.|.:...   |...|.....:|.|...:.|.:..:.|.:.|:          .
Mouse   385 TDFDLDVISLKEEGLEKIGTWDPSSGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKS 449

  Fly    92 DFPLSYTEVLENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSDFD-------RSLIE 149
            |.||...:..|       |....::..|.....||||:.:.:|...|:..|.:       |.||:
Mouse   450 DKPLYGNDRFE-------GYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELID 507

  Fly   150 MVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVM------QRPRESASG-SGLLAPFEF 207
                ...|||.|.:       :..|.....:|..:..|.:      ::|..:..| ...|.|...
Mouse   508 ----HKADLAVAPL-------AITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSP 561

  Fly   208 WVWILILVSLLAVGPIIYALIILRNRLT------------------------------------- 235
            .:|:.||::.|.|..::: :|..:::.:
Mouse   562 DIWMYILLAYLGVSCVLF-VIARQSKFSWFKYPNCSHYHHSQRCLCTQHLESYMELCLFSPYEWY 625

  Fly   236 --------GDGQQTPYSLGHCAWFVYGALMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANL 292
                    .|..:..::|.:..||..||||:|||.|.|.|.|||::...||.|..|:.|.|||||
Mouse   626 NPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANL 690

  Fly   293 TAFLTLSKFTLPYNTVNDILTKNKHFVSMRGGGVEYAIRTT---NESLSMLNRMIQNNYAVFSDE 354
            .||||:.:...|.::.:|:..:.|    :..|.||.....|   ...:|..::|    :|..|..
Mouse   691 AAFLTVERMESPIDSADDLAKQTK----IEYGAVEDGATMTFFKKSKISTYDKM----WAFMSSR 747

  Fly   355 TNDTYNLQNYVEKNGYVFVRDRPAINIMLYRDYLY---RKTVSFSDEKVHCPFAMAKEPFLKKKR 416
            .      |:.:.|:      :...|..:|..||.:   ..|:.|..:: :|...........|..
Mouse   748 R------QSVLVKS------NEEGIQRVLTSDYAFLMESTTIEFVTQR-NCNLTQIGGLIDSKGY 799

  Fly   417 TFAYPIGSNLSQLFDPELLHLVESGIVKHLSKRNLPSAEICPQDLGGTERQLRNGDLMMTYYIML 481
            ....|:||.........:|.|.|.|.: |:.|........||::.......|...::...:.::.
Mouse   800 GVGTPMGSPYRDKITIAILQLQEEGKL-HMMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLA 863

  Fly   482 AGFATALAVFSTELMFRYVNSRQ 504
            ||...::.|...|.:::...:.|
Mouse   864 AGLVLSVFVAVGEFLYKSKKNAQ 886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	91/428 (21%)
Grik2	XP_011241422.1	PBP1_iGluR_Kainate	37..414	CDD:380605	7/28 (25%)
		Periplasmic_Binding_Protein_Type_2	430..835	CDD:389745	96/445 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846435
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840