Protein Alignment Ir76b and Gria4

DIOPT Version :9

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_006509904.1
• Gene: Gria4 / 14802
• MGIID: 95811
• Length: 912
• Species: Mus musculus
• Alignment Length: 483
• Identity: 106/483 - (21%)
• Similarity: 188/483 - (38%)
• Gaps: 108/483 - (22%)

  Fly    88 ATLEDFPLSYTEVLEN-------------GTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGS 139
            |.:|:..:..|.::|:             |.....|....:...:.|.....|::.:..|...|:
Mouse   410 AAIENRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGA 474

  Fly   140 PSDFDRSLIE-MVNS---STVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASG-S 199
             .|.|..:.. ||..   ...::|.|.:.....:...:.:|...:..|..||: ::|::|..| .
Mouse   475 -RDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMI-KKPQKSKPGVF 537

  Fly   200 GLLAPFEFWVWILILVSLLAVGPIIYALIILRNRLT---------GDGQQTP-------YSLGHC 248
            ..|.|..:.:|:.|:.:.:.|..:::    |.:|.:         .||::.|       :.:.:.
Mouse   538 SFLDPLAYEIWMCIVFAYIGVSVVLF----LVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNS 598

  Fly   249 AWFVYGALMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLP--------- 304
            .||..||.|:||..:||.:.|.|::...||.|..|:.|.|||||.||||:.:...|
Mouse   599 LWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK 663

  Fly   305 -----YNTVNDILTK-----------NKHFVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSD 353
                 |.|::...||           .|.:..||........|||.|.::.: |..:..:|...:
Mouse   664 QTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARV-RKSKGKFAFLLE 727

  Fly   354 ETNDTYNLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTF 418
            .|     :..|:|:        |...:.|        |.....|.|.:               ..
Mouse   728 ST-----MNEYIEQ--------RKPCDTM--------KVGGNLDSKGY---------------GV 756

  Fly   419 AYPIGSNLSQLFDPELLHLVESGIVKHL-SKRNLPSAEICPQDLGGTER--QLRNGDLMMTYYIM 480
            |.|.||:|....:..:|.|.|:|::..| :|......|..|:|.|..::  .|...::...:||:
Mouse   757 ATPKGSSLRTPVNLAVLKLSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYIL 821

  Fly   481 LAGFATALAVFSTELMFRYVNSRQEANK 508
            :.|...|:.|...|..::   ||.||.:
Mouse   822 VGGLGLAMLVALIEFCYK---SRAEAKR 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Periplasmic_Binding_Protein_Type_2	83..437	CDD:304360	86/407 (21%)
Gria4	XP_006509904.1	PBP1_iGluR_AMPA_GluR4	28..400	CDD:380611
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	89/423 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846427
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840