Protein Alignment Ir76b and Nmdar1

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_321646.4
• Gene: Nmdar1 / 1281696
• VectorBaseID: AGAMI1_011915
• Length: 966
• Species: Anopheles gambiae
• Alignment Length: 666
• Identity: 148/666 - (22%)
• Similarity: 237/666 - (35%)
• Gaps: 187/666 - (28%)

  Fly    30 QMGENGTLSPVTELPMDVDAS----EAG--------------------FD--ADAPVETLETIN- 67
            :|..|.|   :||.|.|.|.|    |:|                    ||  .|......:.||
Mosquito   306 EMTVNET---ITEAPKDCDDSGVIWESGKRLFGYLKTRNIRGETGQVAFDDNGDRMYAEYDVINV 367

  Fly    68 -----------------RKKPKLR---EMLDWIG--GK---------HLRIATLEDFPLSYTEVL 101
                             ::|.:|:   ..:.|.|  ||         ||::.|:|:.|..|...|
Mosquito   368 HENHSFVKVGSFHYDSEKRKMRLKINDSSITWPGNTGKKPEGIMIPTHLKVLTIEEKPFVYARKL 432

  Fly   102 -------------------ENGTRVGHGVSFQIIDFLK---KKFNFTYEVVVPQDNIIGS----- 139
                               .||....:......||.||   ::.||||::.:..|...|.
Mosquito   433 LDDEIDCADDEVVCPHFNITNGNEQEYCCKGYCIDLLKALAQRINFTYDLALSPDGQFGHYQLKN 497

  Fly   140 ---------PSDFDRSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRES 195
                     ..:::..:.|:| :...||..|.:....::..|:.:|.....:|..|: .::|..|
Mosquito   498 HTTGIGTTVKKEWNGLIGELV-AERADLIVAPLTINPERAEFIEFSKPFKYQGITIL-EKKPSRS 560

  Fly   196 ASGSGLLAPFEFWVWILILVSLLAVGPIIYALIIL----RNRL-TGDG-QQTPYSLGHCAWFVYG 254
            ::....|.||...:|||::||:..|..::|.|...    |.:| |.|| ::...:|....||.:|
Mosquito   561 STLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRFKLSTTDGTEEDALNLSSAIWFAWG 625

  Fly   255 ALMKQG-STLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNK-- 316
            .|:..| ...:|.:.|.|:|...|..|..|:.:.|||||.|||.|.:.......:||...:|.
Mosquito   626 VLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTKLTGINDARLRNTME 690

  Fly   317 --HFVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSDETNDTYNLQNYVEKNG--YVFVRDRP 377
              ...:::|..|:...|...|..:|...|..|||........|.        |:|  ..|:.|..
Mosquito   691 NLTCATVKGSSVDMYFRRQVELSNMYRTMEANNYDTAEQAIQDV--------KDGKLMAFIWDSS 747

  Fly   378 AINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGI 442
            .:.....:|               |....|.|.|.:.........||..:......:|...|||.
Mosquito   748 RLEYEASKD---------------CELVTAGELFGRSGYGVGLQKGSPWTDAVTLAILDFHESGF 797

  Fly   443 VKHLSK--------RNLPSAEICPQDLGGTERQLRNGDLMMTYYIML-AGFATALAVFSTELMF- 497
            ::.|.|        :.....|..|..||     |:|   |...:|:: ||....:.:...|:::
Mosquito   798 MESLDKEWIFHGNVQQCEQFEKTPNTLG-----LKN---MAGVFILVGAGIVGGIGLIIIEVVYK 854

  Fly   498 RYVNSRQEANKWARHGIGRTPNGQSVAPSRWLRG--------------WRRLNSGHGQLLGASTH 548
            ::...:|:..:.|||           |..:| ||              .|:.|.|... :..|..
Mosquito   855 KHQIKKQKKMEIARH-----------AADKW-RGTIEKRKTLRASLAMQRQYNVGLNS-VSKSVQ 906

  Fly   549 GQN-------VTPPPP 557
            .||       :.||.|
Mosquito   907 SQNAEKSRYPILPPLP 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	29/153 (19%)
		Lig_chan	209..458	CDD:459656	66/269 (25%)
Nmdar1	XP_321646.4	None