Protein Alignment Ir76b and Ir76b

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_061511889.1
• Gene: Ir76b / 1280702
• VectorBaseID: AGAMI1_009346
• Length: 658
• Species: Anopheles gambiae
• Alignment Length: 653
• Identity: 316/653 - (48%)
• Similarity: 419/653 - (64%)
• Gaps: 49/653 - (7%)

  Fly    12 ALCVA--CPPLNDSPPTNLIQMGENGTLSPVTELPM--DVDASEAGFDAD--APVE--------- 61
            |||.|  .|..:...|... :.|...|::....:.|  .|..::.|.||.  ||||
Mosquito    23 ALCRAERWPDKDHGDPQRR-RYGMTATVAVALAMMMMIVVATTQLGVDAQGIAPVEWDGNETTEY 86

  Fly    62 -------TLETINRKKPKLREMLDWIGGKHLRIATLEDFPLSYTEVLENGTRVGHGVSFQIIDFL 119
                   :.|...|:..:||..|.   |..||:.||:|:||||| |..|||.:|.||:|::::||
Mosquito    87 YQLEMDASAEVKEREMQELRRRLT---GTTLRVTTLQDWPLSYT-VKINGTYIGAGVAFELLEFL 147

  Fly   120 KKKFNFTYEVVVPQDNIIGSPSDFDRSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGE 184
            .:|||||||:|:|:.||:||.:|...|:::::.:.|.|:|.:|:|.|:|.|..:.|| |.|||||
Mosquito   148 MEKFNFTYELVMPEQNIVGSSNDMAGSVLQLLTNGTADMAVSFLPILADARQHIRYS-TGLDEGE 211

  Fly   185 WIMVMQRPRESASGSGLLAPFEFWVWILILVSLLAVGPIIYALIILRNRLTGDGQQTPYSLGHCA 249
            |||:|.||.||||||||||||...|||||||||||||||||.|:|||:|||.|.:|..|:|.||.
Mosquito   212 WIMIMVRPMESASGSGLLAPFNRDVWILILVSLLAVGPIIYGLLILRHRLTKDKEQIIYTLPHCV 276

  Fly   250 WFVYGALMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTK 314
            ||||||||||||||||..||||:|||:||||||||||||||||||||||||||||.|...|:..|
Mosquito   277 WFVYGALMKQGSTLSPTGDSTRILFASWWIFITILTSFYTANLTAFLTLSKFTLPINNAEDVRRK 341

  Fly   315 NKHFVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSDETNDTYNLQNYVEKNGYVFVRDRPAI 379
            .|.||::|||.:||||:..:|:|:.|:.::......|:...||:..|.:.|.|..||||||||||
Mosquito   342 EKQFVTIRGGAIEYAIKNRDEALNALSVLVDKRLVDFTTNVNDSDTLADKVAKQNYVFVRDRPAI 406

  Fly   380 NIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVK 444
            :.|:|.|||.|:.::..:|:||||:|.|..||||:.|.|.||..:..:::||||||.:||.||||
Mosquito   407 DHMIYADYLVRRKINPKNERVHCPYATATTPFLKRNRAFGYPPNTEWNRIFDPELLKMVEGGIVK 471

  Fly   445 HLSKRNLPSAEICPQDLGGTERQLRNGDLMMTYYIMLAGFATALAVFSTELMFRYVNSR----QE 505
            :.....||.||||||:||||||||:|.||:|||::|:.||.|::.||::||.|||:|.|    |.
Mosquito   472 YKLHDRLPKAEICPQNLGGTERQLKNRDLVMTYFVMVTGFVTSIVVFASELGFRYLNQRKLNEQL 536

  Fly   506 ANKWARHGIGRTPNGQSVAPSRWLRGWRRLNSGHGQLLGASTHGQNVTPPPPYQSIFNGGSHGDP 570
            |.:..:....:.|..:.:|..|.....::..:|.             :|||||..:|:.......
Mosquito   537 AQQQQQQQQDQQPTSKKLATERISYLGKQFTTGD-------------SPPPPYAEVFSRHQQQQQ 588

  Fly   571 LNRWRRPLANGNAL--GNGVLLGGDSEGGV-RRLINGRDYMVFRNPNG-QSQLVPVRSPSAALFQ 631
            |.........|...  |:|.|.|....||. |::||||||||.|..|| .|:|:|:|:||||:|.
Mosquito   589 LGVLGDSERTGKLFDDGSGGLYGAGGAGGANRQMINGRDYMVVREKNGLGSRLIPMRAPSAAIFH 653

  Fly   632 YSY 634
            |:|
Mosquito   654 YTY 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	55/108 (51%)
		Lig_chan	209..458	CDD:459656	151/248 (61%)
Ir76b	XP_061511889.1	None