Protein Alignment Ir76b and Ir25a

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_319463.5
• Gene: Ir25a / 1279695
• VectorBaseID: AGAMI1_004282
• Length: 946
• Species: Anopheles gambiae
• Alignment Length: 564
• Identity: 114/564 - (20%)
• Similarity: 203/564 - (35%)
• Gaps: 122/564 - (21%)

  Fly    26 TNLIQMGENGTLSPV-------------TELPMDVDASEAGFDADAPVETLETINRKKPKLREML 77
            |..|::.|..|..|.             |.:..|:|.:.....:.|.|.| .::...:..|...:
Mosquito   356 TAFIEVTEPTTFGPFEIPKGGKMQFNGNTYMKFDMDINAVSIRSGASVNT-RSLGTWEASLNAPI 419

  Fly    78 DWIGGKHLRIATLEDFPLSYTEV----LENGTRVGHGVSFQIIDFLKK---KFNFTYEVVVPQDN 135
            :......::..|.:.....||.|    :........|.....||.|.|   ...|.||:...:|.
Mosquito   420 NVANEAEIKNLTADVVYRVYTVVQAPFIMRDPTAPKGFKGYCIDLLNKIAEIVEFDYEIREVEDG 484

  Fly   136 IIGSPSD------FDRSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRE 194
            ..|:.::      ..|.||:    ...|:....:..::::.:.:.::....|.....::||.|..
Mosquito   485 KFGNMNENGEWNGIVRKLID----KQADIGLGSMSVMAERETVIDFTVPYYDLVGISIMMQLPST 545

  Fly   195 SASGSGLLAPFEFWVWILILVSLLAVGPII--------YALIILRNRLTGDGQQTPYSLGHCAWF 251
            .:|....|...|..||:.||.:......::        |:....|.:...|.::..:::..|.||
Mosquito   546 PSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRYSPYSYQNNREKYKNDDEKREFNIKECLWF 610

  Fly   252 VYGALMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNK 316
            ...:|..||...:|...|.||:.||||:|..|:.:.|||||.||||:|:...|..:::|:..:.|
Mosquito   611 CMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVESLDDLSKQYK 675

  Fly   317 HFVSMRGGG-----------VE---YAI---RTTNESLSMLNRMIQNNYAVFSDETNDTY----- 359
            ...:...|.           :|   |.|   .:.|:||:.:.|   :..||:....:|.|
Mosquito   676 ILYAPLNGSSAMTYFQRMADIEAKFYEIWKEMSLNDSLTAVER---SKLAVWDYPVSDKYTKMWQ 737

  Fly   360 ----------------NLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVHCPFAMAK 408
                            .::|....:|:.|:.|...|...:.               .:|...|..
Mosquito   738 AMLEAGLPNSLEEAVQRIRNSTSASGFAFLGDATDIRYQVL---------------TNCDLQMVG 787

  Fly   409 EPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHL--------------SKRNLPSAEICPQ 459
            |.|.:|....|...||.|...|:..:|.|:....::.|              .|.:..|..|..|
Mosquito   788 EEFSRKPYAIAVQQGSPLKDQFNNAILMLLNRRELEKLKEQWWKNDDVQNKCEKPDDQSDGISIQ 852

  Fly   460 DLGGTERQLRNGDLMMTYYIMLAGFATALAVFSTEL-MFRYVNS 502
            ::||            .:.::..|...|......|. .::|.|:
Mosquito   853 NIGG------------VFIVIFVGIGMACITLLFEFWYYKYRNN 884

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	21/121 (17%)
		Lig_chan	209..458	CDD:459656	69/308 (22%)
Ir25a	XP_319463.5	None