Protein Alignment Ir76b and LOC1276693

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_061500826.1
• Gene: LOC1276693 / 1276693
• VectorBaseID: AGAMI1_001614
• Length: 972
• Species: Anopheles gambiae
• Alignment Length: 656
• Identity: 138/656 - (21%)
• Similarity: 240/656 - (36%)
• Gaps: 180/656 - (27%)

  Fly    21 NDSPPTNLIQMG--------ENGTLSP---------------VTELPMDVDASEAGFDADAPVET 62
            |...|.||...|        ..|.::|               ::.|..|:..:|.|...:..:..
Mosquito   380 NRGQPFNLPANGTRTLDCNTSKGWVTPWEHGDKISRYLRKVEISGLTGDIRFNEDGKRQNYTLHV 444

  Fly    63 LE-TINRKKPKLREMLDWIG-----GKHLRIATLEDFPLSYT--------------------EVL 101
            :| |:|....|:.|..|..|     .|:.|:.|...:..:.|                    |.|
Mosquito   445 VEMTVNSAMVKVAEWSDEGGLAPVVAKYTRLKTDMHYERNKTYIVTTIIEEPYIMLRQPEPGETL 509

  Fly   102 ENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPS-----DFDRSLIEMVNSSTVDLAAA 161
            |...|. .|....:.:.:.||....||:.:.:|...||.:     .:|..:.|:|... .|.|.|
Mosquito   510 ETNERF-EGYCKDLAELVAKKLGINYELRIVKDGQYGSENPDVKGGWDGMVGELVRKE-ADFAIA 572

  Fly   162 FIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWVWILILVSLLAVGPIIYA 226
            .:...|::...:.:|...:..|..||:.:..::..|....|.|....:|:.:|.|.:.|..::|
Mosquito   573 PMTITSERERVIDFSKPFMSLGISIMIKRPVKQKPSVFSFLNPLSKEIWVCVLFSYVGVSIVLY- 636

  Fly   227 LIILRN-----RLTG-DGQQ---------TPYSLGHCAWFVYGALMKQGSTLSPIADSTRLLFAT 276
             |:.|.     ||.. :|:|         ..:|:.:..||..||.|:||..:||.:.|.|::.:.
Mosquito   637 -IVSRFSPFEWRLVNYNGEQPDAVPQATVNEFSILNSFWFALGAFMQQGCDISPRSISGRIVGSV 700

  Fly   277 WWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDIL--TKNKHFVSMRGGGVEYAIRTTNESLSM 339
            ||.|..||.|.|||||.||||:.:...|.|:..|:.  |:.::...:.|...::..::   .:|:
Mosquito   701 WWFFTLILISSYTANLAAFLTVERMVTPINSPEDLASQTEVQYGTLIHGSTWDFFRKS---QISL 762

  Fly   340 LNRMIQNNYAVFSDETNDTYNLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVS---------- 394
            .:||.:                  |:....::||:.        |.:.:.|...|
Mosquito   763 YSRMWE------------------YMNSRKHLFVKS--------YDEGIRRVRTSKGKYALLIES 801

  Fly   395 ----FSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIV------------ 443
                :::|:..|...........|....|.|:||.|....:..:|.|.|:|.:
Mosquito   802 PKNEYTNEREPCDTMKVGRNLDAKGFGIATPLGSPLRDPINLAVLSLKENGELTKLVNKWWFDRT 866

  Fly   444 --KHLSKRNLPSAEICPQDLGGTERQLRNGDLMMTYYIMLAGFATALAVFSTELMFRYVNSRQEA 506
              ||..|::....|:...::.|            .:||::.|...||||...|...:  :|.:.:
Mosquito   867 ECKHYDKQDASRNELSLSNVAG------------IFYILIGGLLVALAVALVEFCMK--SSNRSS 917

  Fly   507 NKWARHGIGRTPNGQSVAPSRWLRGWRRLNSGHGQLLGASTHGQNVTPPPPYQSIFNG------- 564
            |        |.|...::..:                   |.....:|.||..:...||
Mosquito   918 N--------RIPLSDTMTSN-------------------SNSKNRLTMPPTAREYDNGRIGYYTP 955

  Fly   565 GSHGDP 570
            .:|.||
Mosquito   956 ATHTDP 961

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	27/133 (20%)
		Lig_chan	209..458	CDD:459656	68/293 (23%)
LOC1276693	XP_061500826.1	None