Protein Alignment Ir76b and Nmdar2

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_061504088.1
• Gene: Nmdar2 / 1275196
• VectorBaseID: AGAMI1_003064
• Length: 910
• Species: Anopheles gambiae
• Alignment Length: 700
• Identity: 139/700 - (19%)
• Similarity: 242/700 - (34%)
• Gaps: 223/700 - (31%)

  Fly    54 FDADAPVETLE--------TINRK----------KPKLREMLD-----WIGGK-----------H 84
            |.||..:::.|        ::|.|          |...::.||     |.|..           |
Mosquito   258 FTADGDLKSAELKIMNLRPSVNSKGLVWEEIGIWKSWQQQKLDIRDIAWPGNSHTPPQGVPEKFH 322

  Fly    85 LRIATLEDFP---LSYTEVLENGTRVGHGVSFQI----------------------------IDF 118
            |:|..||:.|   ||..:.:.....:..||..::                            ||.
Mosquito   323 LKITFLEEAPYINLSPADPVSGKCLMDRGVLCRVAADHEMTDIDMGQAHKNGSFYQCCSGFCIDL 387

  Fly   119 LKK---KFNFTYEVVVPQDNIIGSPSD--FDRSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTT 178
            |:|   :..||||:|..:|...|:..:  ::..:.|:||..| |:....:...:::.:.|.:|..
Mosquito   388 LEKFAEELGFTYELVRVEDGKWGTLENGKWNGLIHELVNRKT-DMVLTSLMINAEREAVVDFSEP 451

  Fly   179 TLDEGEWIMVMQRPRESASGSGLLAPFEFWVWILILVSLLAVGPIIYALIILR---------NRL 234
            .::.|..|:|.:| ....|.:..|.||:...|  :||.:.|:....:.:.:..         ..:
Mosquito   452 FMETGIAIVVAKR-TGIISPTAFLEPFDTASW--MLVGIFAIQAATFMIFLFEWLSPSGYDMKTV 513

  Fly   235 TGDGQQTPY--SLGHCAWFVYGALMKQGSTL-SPIADSTRLLFATWWIFITILTSFYTANLTAFL 296
            ..:||.|||  ||....|.|:..|.:....: ||...::|.:...|.:|..:..:.|||||.||:
Mosquito   514 LQNGQTTPYRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWAMFAVVFLAIYTANLAAFM 578

  Fly   297 -------------------------TLSKFTLPYNTVNDILTKNKHFVSMRGGGVEYAIRTTNES 336
                                     |:...|:|::..:.  |.:|:|..|     .|.::..|.|
Mosquito   579 ITREEFHEFTGLDDSRLSHPFSHKPTIKFGTIPWSHTDS--TISKYFKEM-----HYYMKQYNRS 636

  Fly   337 LSMLNRMIQNNYAVFSDETNDTYNLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVH 401
                 .:.....||.|.:.:              .|:.|...:      |||.::     ||  .
Mosquito   637 -----SVADGVTAVLSGQLD--------------AFIYDGTVL------DYLVQQ-----DE--D 669

  Fly   402 CPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKRNLPSAEICPQDLGGTER 466
            |......:.:.......|:...|....:|:..||....:|.::.|  |.......|..  |..|.
Mosquito   670 CRLLTVGQWYAMTGYGLAFSRNSKYVGMFNKRLLEFRANGDLERL--RRFWMTGTCRP--GKQEH 730

  Fly   467 Q----LRNGDLMMTYYIMLAG-FATALAVFSTELMFRYVNSRQEANKWARHGIGRTPNG------ 520
            :    |.....:..:.:::|| ...||.:....|.|:|...|          :.:...|
Mosquito   731 KSSDPLALEQFLSAFLLLMAGILLAALLLLLEHLYFKYFRKR----------LAKKDRGGCCALI 785

  Fly   521 -QSVAPSRWLRG-----------------------WR--------RLNSGHGQLLGASTHGQNVT 553
             .|:..|...||                       |:        ||.:.|.:.. ...||  :.
Mosquito   786 SLSMGKSLTFRGAVYEATEILRRHRCNDPICDTHLWKVKHELDMSRLRNQHLEKT-MQIHG--IK 847

  Fly   554 PPPPYQSIFN-----GGSHG--DPL-NRWRRPLANGNALGNGVLLGGDSE 595
            ||.|.....|     .|:.|  |.: :.:::|    |..|| :.:||.|:
Mosquito   848 PPQPKLGSTNKIIRIAGTTGARDLIDDGYQQP----NLFGN-LSIGGSSQ 892

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	31/155 (20%)
		Lig_chan	209..458	CDD:459656	55/285 (19%)
Nmdar2	XP_061504088.1	None