DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ir76b and LOC1272393

DIOPT Version :10

Sequence 1:NP_649176.1 Gene:Ir76b / 40198 FlyBaseID:FBgn0036937 Length:636 Species:Drosophila melanogaster
Sequence 2:XP_311343.5 Gene:LOC1272393 / 1272393 VectorBaseID:AGAMI1_003669 Length:940 Species:Anopheles gambiae


Alignment Length:448 Identity:100/448 - (22%)
Similarity:176/448 - (39%) Gaps:70/448 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    99 EVLENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSDFDR---SLIEMVNSSTVDLAA 160
            |.||...|. .|.|.::||.:.|...|.|.:.:..|...||.:...:   .|::.:.....|||.
Mosquito   453 EFLEGNNRF-EGYSLELIDGISKILGFQYRMELVPDGKYGSYNKVTKKWDGLVKYLLDRKADLAV 516

  Fly   161 AFIPSLSDQRSFVYYSTTTLDEGEWIMV---MQRPRESASGSGLLAPFEFWVWILILVSLLAVGP 222
            ..:....::|:.|.::...:..|..|:.   :|:|::..|   .|:|....|||.:..:.|.|..
Mosquito   517 CDLTITYERRTAVDFTMPFMTLGISILYAKPVQQPKDLFS---FLSPLSLDVWIYMATAYLGVSV 578

  Fly   223 IIYALIILRNRLTGDGQQTP-------------YSLGHCAWFVYGALMKQGSTLSPIADSTRLLF 274
            :::.|    :|:.....:.|             :.:.:..|...|::|.||..:.|.|.||||:.
Mosquito   579 LLFVL----SRMAPADWENPHPCKQDNDEVENIWDMCNALWLTMGSIMGQGCDILPKAISTRLVA 639

  Fly   275 ATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDIL--TKNKHFVSMRGGGVEYAIRTTNESL 337
            ..||.|..|:.|.|||||.||||:.:......:..|:.  :|.|:.|.| ||......:|:|.|.
Mosquito   640 GMWWFFALIMLSSYTANLAAFLTMERMDATIESAEDLAKQSKIKYGVVM-GGSTMAFFQTSNFST 703

  Fly   338 --SMLNRMIQNNYAVFSDETNDTYNLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKV 400
              .|...|.....:||: ::||....:....|..|.|:.:..::..:..|               
Mosquito   704 YQRMWASMESARPSVFT-KSNDEGRDRVIKGKRMYAFLMESTSLEYITER--------------- 752

  Fly   401 HCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKR------------NLPS 453
            :|...........|....|.|:.|.........:|.:.|.|.:..|..|            .:|:
Mosquito   753 YCDLTQIGGLLDSKGYGIAMPVNSPYRTAISGAVLKMQEEGKLYQLKTRWWKEMRGGGQCTEVPN 817

  Fly   454 AEICPQDLGGTERQLRNGDLMMTYYIMLAGFATALAVFSTELMF--RYVNSRQEANKW 509
            :        ..|.:|..|::...:.::..|...|..:...|.::  |.|...::...|
Mosquito   818 S--------SQENELGIGNVGGVFVVLALGCFCAFLIGILEFLWNVRKVAVEEKVTPW 867

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir76bNP_649176.1 Lig_chan-Glu_bd 83..192 CDD:463166 23/98 (23%)
Lig_chan 209..458 CDD:459656 64/277 (23%)
LOC1272393XP_311343.5 None

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