DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ir76b and LOC1270566

DIOPT Version :10

Sequence 1:NP_649176.1 Gene:Ir76b / 40198 FlyBaseID:FBgn0036937 Length:636 Species:Drosophila melanogaster
Sequence 2:XP_309276.5 Gene:LOC1270566 / 1270566 VectorBaseID:AGAMI1_006865 Length:939 Species:Anopheles gambiae


Alignment Length:441 Identity:99/441 - (22%)
Similarity:174/441 - (39%) Gaps:56/441 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    99 EVLENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSDFDR---SLIEMVNSSTVDLAA 160
            |.||...|. .|.|.::||.:.|...|.|.:.:..|...||.:...:   .|::.:.....|||.
Mosquito   452 EFLEGNNRF-EGYSLELIDGISKILGFQYRMELVPDGKYGSYNKVTKKWDGLVKHLLDRKADLAV 515

  Fly   161 AFIPSLSDQRSFVYYSTTTLDEGEWIMV---MQRPRESASGSGLLAPFEFWVWILILVSLLAVGP 222
            ..:....::|:.|.::...:..|..|:.   :|:|::..|   .|:|....|||....:.|.|..
Mosquito   516 CDLTITYERRTAVDFTMPFMTLGISILYAKPVQQPKDLFS---FLSPLSLDVWIYTATAYLGVSV 577

  Fly   223 IIYALIILRNRLTGDGQQTP-------------YSLGHCAWFVYGALMKQGSTLSPIADSTRLLF 274
            :::.|    :|:.....:.|             :.:.:..|...|::|.||..:.|.|.||||:.
Mosquito   578 LLFVL----SRMAPADWENPHPCKQDNDEVENIWDMLNALWLTMGSIMGQGCDILPKAISTRLVA 638

  Fly   275 ATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNK-HFVSMRGGGVEYAIRTTNESL- 337
            ..||.|..|:.|.|||||.||||:.:......:..|:..::| .:..:.||......:|:|.|. 
Mosquito   639 GMWWFFALIMLSSYTANLAAFLTMERMDATIESAEDLAKQSKIKYGVLMGGSTMAFFQTSNFSTY 703

  Fly   338 -SMLNRMIQNNYAVFSDETNDTYNLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVH 401
             .|...|.....:||: ::||....:....|..|.|:.:..::..:..|               :
Mosquito   704 QRMWASMESVRPSVFT-KSNDEGRDRVIKGKRMYAFLMESTSLEYITER---------------Y 752

  Fly   402 CPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKR---NLPSAEIC---PQD 460
            |...........|....|.|:.|.........:|.:.|.|.:..|..|   .:.....|   |..
Mosquito   753 CDLTQIGGLLDSKGYGIAMPVNSPYRTAISGAVLKMQEEGKLHQLKTRWWKEMRGGGQCTEVPNS 817

  Fly   461 LGGTERQLRNGDLMMTYYIMLAGFATALAVFSTELMF--RYVNSRQEANKW 509
            .|  |.:|..|::...:.::..|...|..:...|.::  |.|...::...|
Mosquito   818 AG--ENELGIGNVGGVFVVLALGCFCAFIIGILEFLWNVRKVAVEEKITPW 866

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir76bNP_649176.1 Lig_chan-Glu_bd 83..192 CDD:463166 23/98 (23%)
Lig_chan 209..458 CDD:459656 61/270 (23%)
LOC1270566XP_309276.5 None

Return to query results.
Submit another query.