Protein Alignment Ir76b and Grik4

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_780690.2
• Gene: Grik4 / 110637
• MGIID: 95817
• Length: 956
• Species: Mus musculus
• Alignment Length: 550
• Identity: 135/550 - (24%)
• Similarity: 216/550 - (39%)
• Gaps: 105/550 - (19%)

  Fly    95 LSYTEVLEN-------------GTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSDFDRS 146
            |..|.:|||             |.....|....::..|.:...|.|::.:..|.:.|.| :.:.:
Mouse   418 LVVTTILENPYLMLKGNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVP-EANGT 481

  Fly   147 LIEMVN---SSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFW 208
            ...||.   :...|||.|.:...:::...:.:|...:..|..|:..............|.||...
Mouse   482 WTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRRPGYFSFLDPFSPG 546

  Fly   209 VWILILVSLLAVGPIIYALIILRNRLTGDGQQTP--------------YSLGHCAWFVYGALMKQ 259
            ||:.:|::.|||..:::    |..|||.....:|              ||||:..||..|..|:|
Mouse   547 VWLFMLLAYLAVSCVLF----LVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQ 607

  Fly   260 GSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNKHFVSMRGG 324
            |||::|.|.|||.:...||.|..|:.|.|||||.||||:.:..:|..:|:|:..:.
Mouse   608 GSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESVDDLADQT--------- 663

  Fly   325 GVEYAIRTTNESLSMLNRMIQNNYAVFSDETNDTY-NLQNYV-EKNGYVFVRD-RPAINIMLYRD 386
            .:||.  |.:...||         ..|.:....|| .:.||: .|...|||:. ...|..:|..:
Mouse   664 AIEYG--TIHGGSSM---------TFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSN 717

  Fly   387 Y--LYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKR 449
            |  |...|::....:.:|...........|......|:||.....||..:|.|.|:..::.| ||
Mouse   718 YAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEIL-KR 781

  Fly   450 NLPSAEICPQDLGGTERQLRNGDLMMTYYIMLAGFATALAVFSTELMFRYVNSRQEANKWA--RH 512
            .......||::.....:.|...::...:.:::.|.  .:|:|...|.|.:.....||::.:  :.
Mouse   782 KWWEGGKCPKEEDHRAKGLGMENIGGIFVVLICGL--IVAIFMAMLEFLWTLRHSEASEVSVCQE 844

  Fly   513 GIGRTPN----GQSVAPSRWLRGWRRLNSGHGQLLGASTHGQNVTPPPPYQSIFNGGSHGDPLNR 573
            .:....|    ..::.|       ||..||.             .||.|            |:..
Mouse   845 MVTELRNIILCQDNIHP-------RRRRSGG-------------LPPQP------------PVLE 877

  Fly   574 WRRPLANGNA-LGNGVLLG-GDSEGGVRRL 601
            .|||  .|.| |.||.|.| |:.:...:||
Mouse   878 ERRP--RGTATLSNGKLCGAGEPDQLAQRL 905

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	22/112 (20%)
		Lig_chan	209..458	CDD:459656	77/267 (29%)
Grik4	NP_780690.2	Periplasmic_Binding_Protein_type1	24..402	CDD:471960
		PBP2_iGluR_kainate_KA1	415..785	CDD:270442	102/392 (26%)
		QRL_CxxC_CxxC	863..927	CDD:469521	19/69 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..956