Protein Alignment Ir76b and grik3

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_031752773.1
• Gene: grik3 / 100498426
• XenbaseID: XB-GENE-6050069
• Length: 919
• Species: Xenopus tropicalis
• Alignment Length: 503
• Identity: 113/503 - (22%)
• Similarity: 197/503 - (39%)
• Gaps: 89/503 - (17%)

  Fly    27 NLIQMGENGTLSPVTELPMDVDASEAGFDADAPVETLETINRKKPKLREMLDWIGGKHLRIATLE 91
            ::|.:.|:|.....|..|.|            .:...||...:.|.:.|.|.   .:.|.:.|:.
 Frog   393 DIISLKEDGLEKVGTWNPSD------------GLNITETARGRGPNISESLT---NRTLIVTTVL 442

  Fly    92 DFPLSYTEVLENGTRVGHGVSFQ--IIDFLKK---KFNFTYEVVVPQDNIIGSPSDFDR--SLIE 149
            :.|  |.....:.|.:.....|:  .||.|||   ...|.|::.:.:|...||..:..:  .|::
 Frog   443 EEP--YVMFKRSDTPLFGKDRFEGFCIDLLKKIAEILGFDYDIRLVEDAKYGSQDEKGQWNGLVK 505

  Fly   150 MVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWVWILIL 214
            .:.....|||.|.:.....:...:.:|...:..|..|:..:....:.|....|.|....:|:.||
 Frog   506 ELIDHKADLAVAPLTITHVREKVIDFSKPFMTLGISILYRKANGTAPSVFSFLNPLSPDIWMYIL 570

  Fly   215 VSLLAVGPIIYALIILR------------NRLTGDGQQTPYSLGHCAWFVYGALMKQGSTLSPIA 267
            ::.|.|..:::  :|.|            |..| |..:..::|.:..||..||||:|||.|.|.|
 Frog   571 LAYLGVSCVLF--VIARFSPYEWYDAHPCNPGT-DVVENNFTLLNSFWFAVGALMQQGSELMPKA 632

  Fly   268 DSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNKHFVSMRGGGVEYAIRT 332
            .|||::...||.|..|:.|.|||||.||||:.:.....::.:|:..:.|         :||....
 Frog   633 LSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMESAIDSADDLAKQTK---------IEYGAVV 688

  Fly   333 TNESLSMLNRMIQNNYAVFSDETNDTYNLQNYVEKNGYVFVRDRPA---------INIMLYRDY- 387
            ...:::...:   ::.:.|              ||. :.|:..||:         |..:|..||
 Frog   689 DGATMNFFKK---SHISTF--------------EKM-WAFMSSRPSALVKSNEEGIQRVLSADYA 735

  Fly   388 -LYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKR-- 449
             |...|......:.:|...........|......|:||.........:|.|.|:..:..:.:|
 Frog   736 LLMESTAIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDRISIAILQLQEADEIHKMKERWW 800

  Fly   450 ---------NLPSAEICPQDLGGTERQLRNGDLMMTYYIMLAGFATAL 488
                     |..::.:..|::||....|..| |:::..:.:|.|...|
 Frog   801 RSGGCPEEKNKEASALGIQNMGGIFIVLAGG-LILSVVVAMAEFVYKL 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	24/115 (21%)
		Lig_chan	209..458	CDD:459656	66/282 (23%)
grik3	XP_031752773.1	PBP1_iGluR_Kainate	37..417	CDD:380605	6/35 (17%)
		Periplasmic_Binding_Protein_Type_2	433..801	CDD:473866	92/399 (23%)