Protein Alignment Ir76b and grik5

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_002936446.1
• Gene: grik5 / 100497490
• XenbaseID: XB-GENE-953974
• Length: 995
• Species: Xenopus tropicalis
• Alignment Length: 581
• Identity: 135/581 - (23%)
• Similarity: 225/581 - (38%)
• Gaps: 104/581 - (17%)

  Fly    62 TLETINRKKPKLREMLDWIGGKHLRI----------ATLEDFPLSYTEVLEN------------- 103
            ||..:.:.....||:..|...:.|.:          .|||:..|..|.:|||
 Frog   378 TLRILEKAGDGHREIGVWYSNRTLAMNATSLDLSTSETLENKTLVVTTILENPYMMRKSNYRSLS 442

  Fly   104 GTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSP---SDFDRSLIEMVNSSTVDLAAAFIPS 165
            |.....|...:::..|.....|.|::.:.:|.:.|:|   ..:...:.|::|.. .|||.|....
 Frog   443 GNDQYEGFCAEMLMELAALLRFNYKIKLVEDGLYGAPEPNGSWTGMVGELINRK-ADLAVAAFTI 506

  Fly   166 LSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFEFWVWILILVSLLAVGPIIYALIIL 230
            .:::...:.:|...:..|..|:...:..........|.||...||:.:|::.|||..:::    |
 Frog   507 TAEREKVIDFSKPFMTLGISILYRVQMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLF----L 567

  Fly   231 RNRLTGDGQQTP--------------YSLGHCAWFVYGALMKQGSTLSPIADSTRLLFATWWIFI 281
            ..||:......|              |:||:..||..|..|:|||.:.|.|.|||.:...||.|.
 Frog   568 AARLSPYEWYNPHPCLRERHHILENQYTLGNSLWFPVGGFMQQGSEVMPRALSTRCVSGVWWAFT 632

  Fly   282 TILTSFYTANLTAFLTLSKFTLPYNTVNDILTK-NKHFVSMRGGGVEYAIRTTNESLSMLNRMIQ 345
            .|:.|.|||||.||||:.:..:|..:.:|:..: |..:.::.||
 Frog   633 LIIISSYTANLAAFLTVQRMEVPIESADDLADQTNIEYGTIHGG--------------------- 676

  Fly   346 NNYAVFSDETNDTY-NLQNYV-EKNGYVFVRD-RPAINIMLYRDY--LYRKTVSFSDEKVHCPFA 405
            :....|.:....|| .:.||: .|...|||:. ...|..:|...|  |...|::....:::|...
 Frog   677 STMTFFQNSRYQTYQRMWNYMNSKQPSVFVKSTEEGIARVLNSRYAFLLESTMNEYHRRLNCNLT 741

  Fly   406 MAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKRNLPSAEICP------------ 458
            ........|......|:||.........:|.|.|:..::.| ||.......||
 Frog   742 QIGGLLDTKGYGIGMPLGSPYRDEITLAILQLQENNRLEIL-KRKWWEGGKCPKEEDHRAKGLGM 805

  Fly   459 QDLGGTERQLRNGDLMMTYYIMLAGF--ATALAVFSTEL-----MFRYVNSRQEANKWARHGIGR 516
            :::||....|..| |::..::.:..|  :|..:|.:.|:     |...:.|.....|.:|....|
 Frog   806 ENIGGIFVVLICG-LIIAVFVAIMEFVWSTRRSVDNEEISVCQEMLSELRSAVSCKKTSRSRHRR 869

  Fly   517 TP----NGQS-VAPSRWLRGWRRLNSGHGQLLGASTHGQNVTPPPPYQSIFNGGS--HGDP 570
            .|    :|:: ::.||..|..|.....:|:|.....|    .|.||:.....|..  |.||
 Frog   870 RPPRHLHGRTLLSLSRPPRSTRETRLCNGRLYQTHQH----PPAPPHPPPAPGAQRLHEDP 926

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	26/134 (19%)
		Lig_chan	209..458	CDD:459656	69/268 (26%)
grik5	XP_002936446.1	PBP1_iGluR_Kainate_KA1_2	27..405	CDD:380616	6/26 (23%)
		Periplasmic_Binding_Protein_Type_2	418..788	CDD:473866	94/396 (24%)