Protein Alignment Ir76b and grid2

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_031759030.1
• Gene: grid2 / 100487676
• XenbaseID: XB-GENE-955038
• Length: 1007
• Species: Xenopus tropicalis
• Alignment Length: 479
• Identity: 120/479 - (25%)
• Similarity: 203/479 - (42%)
• Gaps: 77/479 - (16%)

  Fly    15 VACPPLNDSP---PTNLIQMGENGTLSPVTELPMDVDASEAGFDADAPVETL-----ETINRKKP 71
            :.|...|..|   ..::::..:.|.:|.:|..   :|.||.|.:.:...|.|     |.:.|...
 Frog   353 LTCIRKNSKPWQGGRSMLETVKKGGVSGLTGA---LDFSEDGGNPNIYFEILGTNYGEELGRGIR 414

  Fly    72 KL---------------REMLDWIGGKHLRIATLEDFPLSYTEVLEN---GTRVGHGVSFQIIDF 118
            ||               |::.:.:.|..||:||:.:.|  :..|.||   ..:...|.|..::|.
 Frog   415 KLGFWNPVTGLNGSLTDRKLENNMRGVVLRVATVLEEP--FVMVSENVLGKPKKYQGFSIDVLDA 477

  Fly   119 LKKKFNFTYEVVVPQDNIIGSPSDFDRS---LIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTL 180
            |.....|.||:.|..|:..||| ..|.|   ||..:.....|:..:.:....|:.:.|.::|..:
 Frog   478 LSSYLGFKYEIYVASDHKYGSP-QADGSWNGLIGELLLKRADMGISALTITPDRENVVDFTTRYM 541

  Fly   181 DEGEWIMVMQRPRESASGSGLLAPFEFWVWILILVSLLAVGPIIYALIILRNRLTGDGQQTPYSL 245
            |....:: :::..::......||||:..:|..|..::|.||.::|.|..|.......|..|..:|
 Frog   542 DYSVGVL-LRKAEKTVDMFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNPPRLQMGSMTSTTL 605

  Fly   246 GHCAWFVYGALMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKF--------- 301
            .:..|||||:.::||..:.....:||::...||:|..|:.|.|||||.||||:|:.
 Frog   606 YNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLTISRIESSIQSLQD 670

  Fly   302 -----TLPYNTVNDILTKNKHFVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSDETNDTYNL 361
                 .:||.||.|    :..:..:|..|:....|  :...|.:.|||..:.   ..|.|...:|
 Frog   671 LSRQTDIPYGTVFD----SAVYEHVRVKGMNPFER--DSMYSQMWRMINRSN---GSENNVQESL 726

  Fly   362 QNY--VEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGS 424
            :..  |:...|.||.|...:      :|     ::.:|:  .|.|.........:....|...||
 Frog   727 EGIQKVKHGNYAFVWDAAVL------EY-----IAINDQ--DCSFYTVGNTIADRGYGIALQHGS 778

  Fly   425 NLSQLFDPELLHLVESG---IVKH 445
            ....:|...:|.|.::|   |:||
 Frog   779 PYRDIFSQRILELQQNGDMDILKH 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	29/114 (25%)
		Lig_chan	209..458	CDD:459656	69/256 (27%)
grid2	XP_031759030.1	Periplasmic_Binding_Protein_type1	28..429	CDD:471960	16/78 (21%)
		PBP2_iGluR_delta_2	440..806	CDD:270449	103/389 (26%)