Protein Alignment Ir76b and grik3

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_017206939.1
• Gene: grik3 / 100334689
• ZFINID: ZDB-GENE-211021-1
• Length: 991
• Species: Danio rerio
• Alignment Length: 532
• Identity: 109/532 - (20%)
• Similarity: 207/532 - (38%)
• Gaps: 111/532 - (20%)

  Fly    63 LETINRKKPKLREMLDWIGGKHLRIA------------TLEDFPLSYTEVLE---------NGTR 106
            |:.::.|:..|:::..|.....|.|.            :|.:..|..|.:||         :...
Zfish   385 LDIVSLKEDGLQKVGKWSASGGLNITEVPRQNGMNITDSLSNRSLVITTILEEPYVMLKKSDKAL 449

  Fly   107 VGH----GVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSDFDR--SLIEMVNSSTVDLAAAFIPS 165
            ||:    |....::..|.....|:||:.:..|...|...|..:  .:|..:.....|||.|.:..
Zfish   450 VGNDRFEGFCIDLLKELASILGFSYEIHLVPDGKYGFQDDKGQWNGMIRELMEHRADLAVAPLTI 514

  Fly   166 LSDQRSFVYYSTTTLDEGEWIMVMQRPRESASG-SGLLAPFEFWVWILILVSLLAVGPIIYALII 229
            ...:...:.:|...|:.|..|: .::|..:.|| ...|.|....:|:.||::.|.|..:::.:.
Zfish   515 TFMREKAIDFSKPFLNTGISIL-YRKPNSTNSGFFSFLNPMTPDIWVYILLAYLGVSCVLFVIA- 577

  Fly   230 LRNRLT-------------GDGQQTPYSLGHCAWFVYGALMKQGSTLSPIADSTRLLFATWWIFI 281
               |.:             .|..:..::|.:..||..|:||:|||.|.|.|.|||::...||.|.
Zfish   578 ---RFSPYEWYDAHPCNPGSDVVENNFTLLNSFWFGVGSLMQQGSELMPKALSTRIIGGIWWFFT 639

  Fly   282 TILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNKHFVSMRGGGVEYAIRTTNESLSMLNR---- 342
            .|:.|.|||||.||||:.:...|.::.:|:..:.|         :||.:.....::|...:
Zfish   640 LIIISSYTANLAAFLTVERMDSPVDSADDLAKQTK---------IEYGVVKDGATMSFFKKSRVS 695

  Fly   343 MIQNNYAVFSDETNDTY--NLQNYVE---KNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVHC 402
            ..:..:|..|...:.::  ::::.::   |:.|..:.:...|      :|:.|:         :|
Zfish   696 TFEKMWAFMSSRQSTSFVKSIEDGIQRVLKSDYALLMESTTI------EYVTRR---------NC 745

  Fly   403 PFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKRNLPSAEICPQD------- 460
            ...........|......|.||.........:|.::|.|.: |:.|....|...|.:|
Zfish   746 NLTQVGGIIDSKGYGIGTPKGSPYRDKITIAILGILEDGRL-HMLKEKWWSGSSCLEDERYETGP 809

  Fly   461 -----LGGTERQLRNGDLMMTYYIMLAGFATALAVFSTELMFRYVNSRQEANKWARHGIGR---- 516
                 |||            .:.::.:|...::.|...|.:::...:.:....:.:.|.||
Zfish   810 MGIQNLGG------------IFIVLASGLVLSVFVAIGEFIYKLRKTAEREQVFLQCGDGRDQTV 862

  Fly   517 ---TPNGQSVAP 525
               ...|::.||
Zfish   863 VHVRETGEAQAP 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	26/135 (19%)
		Lig_chan	209..458	CDD:459656	60/270 (22%)
grik3	XP_017206939.1	PBP1_iGluR_Kainate	32..410	CDD:380605	5/24 (21%)
		Periplasmic_Binding_Protein_Type_2	426..794	CDD:473866	87/397 (22%)