DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ir76b and grik6

DIOPT Version :10

Sequence 1:NP_649176.1 Gene:Ir76b / 40198 FlyBaseID:FBgn0036937 Length:636 Species:Drosophila melanogaster
Sequence 2:XP_021335521.1 Gene:grik6 / 100151589 ZFINID:ZDB-GENE-130530-729 Length:465 Species:Danio rerio


Alignment Length:457 Identity:99/457 - (21%)
Similarity:173/457 - (37%) Gaps:86/457 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    83 KHLRIATLEDFPLSYTEVLENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIGSPSDFD--R 145
            :.|.:.|::..|  ||  :..|::: .|....::..|.||..|.|:|.:.:|...|...:..  .
Zfish    29 QELIVTTIKQDP--YT--MSKGSQL-EGYCMDLLTELAKKLGFKYKVHLVKDGSYGRQDENGNWN 88

  Fly   146 SLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRP---RESASGSGLLAPF-- 205
            .:|..|.....|||.|.:...:.:...|..:...:..|  |.::.|.   .|.|.....|:||  
Zfish    89 GMIGEVVRGEADLAVAPLTLTAAREKAVGMTKPYMQTG--ISILLRKDIVSEEAGFFDFLSPFSG 151

  Fly   206 EFWVWILILVSLLAVGPIIYALIILRNRLT------GDGQQTPYSLGHCAWFVYGALMKQGSTLS 264
            |.|..|||...:.||      .|.:..||:      .:.:...::|.|..|:..|||..||:...
Zfish   152 ETWFGILIAYFVTAV------CICIVGRLSPCEWSQPETEPNHFTLLHSLWYTAGALSLQGAGPH 210

  Fly   265 PIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNKHFVSMRGGGVEYA 329
            |.|.|.|::..|||:|..:|.:.|.::|::........|......|:..::.         :||.
Zfish   211 PKAVSGRVISCTWWLFAVVLLACYFSSLSSTQGSDSAPLMIKGFEDLANQDV---------IEYG 266

  Fly   330 IRTTNESLSMLNRMIQNNYAVFSDETNDTY---------------NLQNYVEK---NGYVFVRDR 376
            ....:.:|           |.|.:..|.:|               ::...|:|   ..|.|:.:.
Zfish   267 TLAGSSTL-----------AFFKNSNNPSYRRIYEHMERRKSFVSSMDEGVQKAKEGNYAFIGES 320

  Fly   377 PAINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVESG 441
            .::::.:.|               ||....|.|....:..:...|:||.:.:.....:|.|.|:|
Zfish   321 VSLDLAVAR---------------HCELVRAHEVIGMRGYSIVTPLGSAMLKNLSVAILQLSEAG 370

  Fly   442 IVKHLSKRNLPSAEICPQDLGGTERQLRNGDLMMTYYIMLA---GFATALAVFSTELMFRYVNSR 503
            .:.:|  |....|..|..| ......|| ...|...:::||   |....|::|......|.....
Zfish   371 ELAYL--RTKWWASSCLPD-NAKASSLR-AHSMKGIFLVLAIGLGIGVLLSLFELTTKSRSAAGE 431

  Fly   504 QE 505
            |:
Zfish   432 QK 433

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir76bNP_649176.1 Lig_chan-Glu_bd 83..192 CDD:463166 24/110 (22%)
Lig_chan 209..458 CDD:459656 55/272 (20%)
grik6XP_021335521.1 PBP2_iGluR_non_NMDA_like 28..381 CDD:270403 86/401 (21%)

Return to query results.
Submit another query.