Protein Alignment Ir76b and grin2db

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_073782035.1
• Gene: grin2db / 100149482
• ZFINID: ZDB-GENE-100920-7
• Length: 1984
• Species: Danio rerio
• Alignment Length: 651
• Identity: 134/651 - (20%)
• Similarity: 234/651 - (35%)
• Gaps: 203/651 - (31%)

  Fly    83 KHLRIATLEDFPLSYTEVLE-----------------NGTRVGHGVS----------FQIIDFLK 120
            :|||:.|||:.|....|:.:                 |.:.:..||:          ..|:..|.
Zfish   458 QHLRVVTLEERPFVIVELADAASGTCIRDSVPCRRPLNASALQEGVAPVKQCCKGFCIDILKRLA 522

  Fly   121 KKFNFTYEVVVPQDNIIGSPSD-FDRSLIEMVNSSTVDLAAAFIPSLSDQRS-FVYYSTTTLDEG 183
            :...|||::.:..:...|...| ....::..|.....|:|...: :::::|| .|.:|...::.|
Zfish   523 RIVGFTYDLYLVTNGKHGKKIDGVWNGMVGEVVYKRADMAIGSL-TINEERSEVVDFSVPFVETG 586

  Fly   184 EWIMVMQRPRESASGSGLLAPFEFWVWILILVSLLAV-----------GPIIYALIILRNRLTGD 237
            ..:|| .|...:.|.|..|.|:...||:::.|..|.|           .|:.|      ||....
Zfish   587 ISVMV-SRSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFIFEFFSPVGY------NRSLQS 644

  Fly   238 GQQ---TPYSLGHCAWFVYGALMKQGSTL-SPIADSTRLLFATWWIFITILTSFYTANLTAFLTL 298
            |::   :.:::|...|.::..:......: :|...:::::...|..|..|..:.|||||.||:..
Zfish   645 GKKAGGSKFTIGKSIWLLWALVFNNSVPVENPKGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQ 709

  Fly   299 SKFTLPYNTVNDILTKN-KH---------FVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSD 353
            .::   .:||:.:..|. :|         |.::..|..|..||:        |....:.|.|
Zfish   710 EEY---IDTVSGLSDKKFQHPTEQYPPLKFGTVPNGSTEKNIRS--------NYPDMHQYMV--- 760

  Fly   354 ETNDTYNLQNYVE------KNGYV--FVRDRPAINIMLYRDYLYRKTVSFSDEKVHCP--FAMAK 408
                .|| |..||      |.|.:  |:.|...:|.|..:|. ..|.::....||...  :.:|
Zfish   761 ----KYN-QKSVEDAISHLKTGKLDAFIYDAAVLNYMARKDE-GCKVMTIGSGKVFATTGYGIA- 818

  Fly   409 EPFLKKKRTFAYPIGSNLSQLFDPELLHLVE----SGIVKHLSKRNLPSAEICPQDLGGTERQLR 469
               |.|...:..|:...|.||...:.:.::|    |||. |..|..:.|:::...::.|
Zfish   819 ---LIKNSRWKRPLDLALLQLVGDDEIEMLERLWLSGIC-HNDKIEVMSSKLDIDNMAG------ 873

  Fly   470 NGDLMMTYYIMLAGFATALAVFSTE-LMFRYVNSRQEANKW-ARHGIGRTPNGQS------VAPS 526
                  .:|::|.....:|.||:.| |::           | .||.:.:.  |||      :|.|
Zfish   874 ------VFYMLLVAMGLSLLVFAWEHLVY-----------WRLRHCMSKM--GQSGKLDFLLAFS 919

  Fly   527 RWL-----------RGWRRLN-SGHGQLLGASTHGQNVT------------------------PP 555
            |.:           :|..::. |||.......|...:|.                        ||
Zfish   920 RGMYSCCSFEDETAQGGAKVTVSGHHHTAMVPTSSSHVVTSAVSNPAIAMVQQQQQQQPQQPQPP 984

  Fly   556 PPYQS--------IFNGGSHGDPLN-------------------------RWRRPLANGNALGNG 587
            ..|::        |.:.|:...|.|                         |||.|...|.....|
Zfish   985 QSYKTPLPGSPPPIVHSGAALGPANTQLIGAPLPCTTFLPRPDRRLAVVDRWRLPKTAGATTSMG 1049

  Fly   588 V 588
            |
Zfish  1050 V 1050

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	28/137 (20%)
		Lig_chan	209..458	CDD:459656	64/287 (22%)
grin2db	XP_073782035.1	None