Protein Alignment Ir76b and grid1

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001096470.1
• Gene: grid1 / 100125089
• XenbaseID: XB-GENE-990290
• Length: 1009
• Species: Xenopus tropicalis
• Alignment Length: 706
• Identity: 158/706 - (22%)
• Similarity: 252/706 - (35%)
• Gaps: 204/706 - (28%)

  Fly    40 VTELPMDVDASEAGFDADAPVETL-----ETINRKKPKLREMLDW------------------IG 81
            :|.|...::..|||.:.....|.|     ||..:   .:|.:..|                  :.
 Frog   375 ITGLTGIMEFKEAGANPHVQFEILGTSYSETFGK---DVRRLATWDSMKGFNGSLQEKPLNNDLQ 436

  Fly    82 GKHLRIATL--EDFPLSYTEVLENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIG---SPS 141
            |..|::.|:  |.|.:....:|....|. .|.|.:|:|.|..:..|.||:....|...|   |..
 Frog   437 GLTLKVVTVLEEPFVMVAENILGQPKRY-KGFSIEILDELSNRLGFKYEIYQAPDGKYGHQLSNG 500

  Fly   142 DFDRSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAPFE 206
            .::..:.|::| ...|:|.:.|....::.:.|.::...||....|:: ::|.|..:...|.|||:
 Frog   501 SWNGMIGELIN-KRADIAISAITITPERENVVDFTKRYLDYSVGILI-KKPEERINIFSLFAPFD 563

  Fly   207 FWVWILILVSLLAVGPIIYALIILRNRL--------TGDGQQTPYSLGHCAWFVYGALMKQGSTL 263
            |.||..|    .||.|::..||.:.||:        :...|.|..:|....|.||||.::||...
 Frog   564 FAVWACI----AAVIPVVGVLIFVLNRIQAVRAQNSSQTSQSTSSTLHSAIWIVYGAFVQQGGES 624

  Fly   264 SPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKF--------------TLPYNTVND---- 310
            :..:.:.|::..:||:|..|:.|.|||||.||||:|:.              .|||.||.|
 Frog   625 AANSVAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLAKQVDLPYGTVKDSSVY 689

  Fly   311 ---------ILTKNKHFVSM-----RGGGVEYAIRTTNESLSMLNRMIQNNYAVFSDETNDTYNL 361
                     .|.:::.|..:     :..|.:..:.:.:|.:....|   .|||...|.|...|
 Frog   690 EYFKSKGTNTLVQDRTFAELWRTIGKNNGSDNCVSSPSEGIRKAKR---GNYAFLWDVTVVEY-- 749

  Fly   362 QNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNL 426
                                           .:.:|::  |..|:.......|....|...||..
 Frog   750 -------------------------------AALTDDE--CSVAVTGNTISSKGYGIALQHGSPY 781

  Fly   427 SQLFDPELLHLVESGIVKHLSKRNLPSAEICPQDLGGTERQLRNGDLMM------TYYIMLAGFA 485
            ..:|...:|...:||.:..|.::..|....|  ||........:|..:.      .:.|:..|..
 Frog   782 RDIFSQRILEFQDSGRLDVLKEKWWPRTGRC--DLNSHNNAQNDGKALKLHSFAGVFCILAIGLL 844

  Fly   486 TALAVFSTELMFRYVNSRQEANKWARHGIGRTPNGQSVAPSRWLRGWRRLNS------GHGQLLG 544
            .|..|.:.||.:.....||::.|     ..:..|.:.|        .|||||      .|.|:..
 Frog   845 LACLVAALELWWNSNRCRQDSPK-----EDKEVNLEQV--------HRRLNSLIDEDMAHKQIST 896

  Fly   545 ASTH----------GQNVTPPPPYQSI-------------FNGG-------SHGDPLNRWRRPLA 579
            ||..          .|.:.|...|||.             .:||       |...||     ||:
 Frog   897 ASIEISALEIGGMPSQTLEPLREYQSTQLSVTTFLPEQTGHSGGRTLTSIPSSNLPL-----PLS 956

  Fly   580 NGNALGNGVLLGGDSEGGVRRLINGRDYMVFRNPNG----QSQLVPVRSPSAALFQ 631
            :...:.:                   .....|:|||    ||   ||::|....||
 Frog   957 SSATMPS-------------------MQCKHRSPNGGLFRQS---PVKTPMPLSFQ 990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	26/113 (23%)
		Lig_chan	209..458	CDD:459656	66/288 (23%)
grid1	NP_001096470.1	PBP1_iGluR_delta_1	25..426	CDD:380615	11/53 (21%)
		PBP2_iGluR_delta_1	437..807	CDD:270448	99/414 (24%)