Protein Alignment Ir76b and grin1b

DIOPT Version :10

• Sequence 1: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001137603.1
• Gene: grin1b / 100005675
• ZFINID: ZDB-GENE-051202-2
• Length: 937
• Species: Danio rerio
• Alignment Length: 623
• Identity: 120/623 - (19%)
• Similarity: 228/623 - (36%)
• Gaps: 158/623 - (25%)

  Fly    26 TNLIQMG-ENGTLSPVTELPMDVDASEAGFDADAPV-----ETLETINRKKPKLREMLDWIGGKH 84
            |.|:|:| .||              |:...:|...:     ||      :|||..:|     ...
Zfish   376 TRLVQVGVYNG--------------SQVVMNAQRKIIWPGGET------EKPKGYQM-----STR 415

  Fly    85 LRIATLEDFPLSYTE-VLENGT----RVGHGVSFQ------------------------IIDFLK 120
            |:|.|:...|..|.: .|.:||    ...:||..:                        .||.|.
Zfish   416 LKIVTIHQEPFVYVKPTLRDGTCKEEHTVNGVKIKKVICTGPNETIPGRPIVPQCCYGFCIDLLI 480

  Fly   121 K---KFNFTYEVVVPQDNIIGSPSDFDRS-------LIEMVNSSTVDLAAAFIPSLSDQRSFVYY 175
            |   ..||||||.:..|...|:....:.|       ::..:.|...|:..|.:...:::..::.:
Zfish   481 KLAFTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGLADMIVAPLTINNERAQYIEF 545

  Fly   176 STTTLDEGEWIMVMQR-PRESASGSGLLAPFEFWVWILILVSLLAVGPIIYALIILRNRLTGDG- 238
            |.....:|..|:|.:. ||.:.  ...:.||:..:|:|:.:|:..|..::|.|    :|.:..|
Zfish   546 SKPFKYQGLTILVKKEIPRSTL--DSFMQPFQSTLWLLVGLSVHVVAVMLYLL----DRFSPFGR 604

  Fly   239 --------QQTPYSLGHCAWFVYGALMKQG-STLSPIADSTRLLFATWWIFITILTSFYTANLTA 294
                    ::...:|....||.:|.|:..| ...:|.:.|.|:|...|..|..|:.:.|||||.|
Zfish   605 FKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAA 669

  Fly   295 FLTLSKFTLPYNTVNDILTKNKH----FVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSDET 355
            ||.|.:.......:||...:|..    :.:::...|:...|...|..:|...|.::||...::.
Zfish   670 FLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEA- 733

  Fly   356 NDTYNLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAY 420
                 :|...:...:.|:.|...:..               :....|......|.|.:.    .:
Zfish   734 -----IQAVRDNKLHAFIWDSAVLEF---------------EASQKCDLVTTGELFFRS----GF 774

  Fly   421 PIG----SNLSQLFDPELLHLVESGIVKHL-----------SKRNLPSAEICPQDLGGTERQLRN 470
            .||    |...|.....:|...|:|.::.|           |:.|.| |.:..:::.|
Zfish   775 GIGMRKDSPWKQNVSLAILSSHENGFMEDLDKTWVRYQECDSRSNAP-ATLTFENMAG------- 831

  Fly   471 GDLMMTYYIMLAGFATALAVFSTELMF-RYVNSRQE--------ANKWARHGIGRTPNGQSVAPS 526
                 .:.::..|....:.:...|:.: |:.::|::        .|.| |..:....:|::....
Zfish   832 -----VFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVW-RKNLQDRKSGRAEPDP 890

  Fly   527 RWLRGWRRLNSGHGQLLGASTHGQNVTPPPPYQSIFNG 564
            :....:|.:::.    |.::...:..:...||.:...|
Zfish   891 KKKASFRSISTN----LASNIKRRRSSKDTPYPTDITG 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	30/148 (20%)
		Lig_chan	209..458	CDD:459656	58/277 (21%)
grin1b	NP_001137603.1	PBP1_iGluR_NMDA_NR1	22..401	CDD:380602	8/38 (21%)
		PBP2_iGluR_NMDA_Nr1	413..815	CDD:270437	88/432 (20%)
		CaM_bdg_C0	851..879	CDD:402271	5/28 (18%)