Protein Alignment CG14185 and DRC3

DIOPT Version :9

• Sequence 1: NP_649175.1
• Gene: CG14185 / 40197
• FlyBaseID: FBgn0036936
• Length: 402
• Species: Drosophila melanogaster
• Sequence 2: XP_011522320.1
• Gene: DRC3 / 83450
• HGNCID: 25384
• Length: 562
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 52/237 - (21%)
• Similarity: 94/237 - (39%)
• Gaps: 38/237 - (16%)

  Fly    92 LLPVVLPQQGPEPTLDELLRRVTQRTDLEAVEQVRLR-VISYTVSLSRLSLFLPR---------- 145
            :|.:.:..|||:....:|.::          |.:..: |:|..:...|.:...|:
Human    17 MLKLAVGDQGPQEEAGQLAKQ----------EGILFKDVLSLQLDFRRKTADEPKGEQDDGQEDS 71

  Fly   146 ---------------LQSLDLSGSVLSSLRDLGYGLLQLTRLDISNCGLNSFDGTSGLPAIRVLI 195
                           |:.|.|..:::..:..| ..|..|..||:|...:.:.:|...|..:..|.
Human    72 QEDILRIDNLWQFENLRKLQLDNNIIEKIEGL-ENLAHLVWLDLSFNNIETIEGLDTLVNLEDLS 135

  Fly   196 ADGNMIQRVDPLAELVHLRVLKARNNRISELGLLSFLGMCPQLQEVELQGNPVCRLPLYRSLLAR 260
            ...|.|.::|.|..||.|:||...||||..:..:.:|.....|:.:.|..||:.....|:..:..
Human   136 LFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA 200

  Fly   261 SVPTLQLLDGRVLNGEPAPVEMEEATSPASSDLESGSETTAQ 302
            .:|.|..||.|.::...|.|.: ..:.|..:|..|..:..|:
Human   201 YLPDLMYLDYRRIDDHTASVSL-SVSQPCETDSSSPQKKLAE 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14185	NP_649175.1	LRR_8	144..201	CDD:290566	14/81 (17%)
		leucine-rich repeat	146..168	CDD:275380	5/21 (24%)
		LRR_4	168..209	CDD:289563	11/40 (28%)
		leucine-rich repeat	169..190	CDD:275380	6/20 (30%)
		leucine-rich repeat	191..212	CDD:275380	6/20 (30%)
		leucine-rich repeat	213..237	CDD:275380	8/23 (35%)
DRC3	XP_011522320.1	leucine-rich repeat	87..108	CDD:275378	5/21 (24%)
		LRR_9	88..213	CDD:317038	35/125 (28%)
		leucine-rich repeat	109..130	CDD:275378	6/20 (30%)
		leucine-rich repeat	131..152	CDD:275378	6/20 (30%)
		leucine-rich repeat	153..177	CDD:275378	8/23 (35%)
		leucine-rich repeat	178..189	CDD:275378	4/10 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810