DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG14185 and CEP97

DIOPT Version :9

Sequence 1:NP_649175.1 Gene:CG14185 / 40197 FlyBaseID:FBgn0036936 Length:402 Species:Drosophila melanogaster
Sequence 2:NP_078824.2 Gene:CEP97 / 79598 HGNCID:26244 Length:865 Species:Homo sapiens


Alignment Length:241 Identity:59/241 - (24%)
Similarity:104/241 - (43%) Gaps:45/241 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 VAIAEEEQHLP----AFVHLLPVVLPQQGP----EPTLDELLRRVTQRTDLEAVEQVRLRVISYT 133
            :|:|..:..||    :.|:.....|.:.||    |..:..|:....|...||.:|:.: |:|..:
Human     1 MAVARVDAALPPGEGSVVNWSGQGLQKLGPNLPCEADIHTLILDKNQIIKLENLEKCK-RLIQLS 64

  Fly   134 VSLSRL-------------SLFLP--------------RLQSLDLSGSVLSSLRDLGYGLLQLTR 171
            |:.:||             .|.||              .|:.|:|:|:.|.::..:. ....|..
Human    65 VANNRLVRMMGVAKLTLLRVLNLPHNSIGCVEGLKELVHLEWLNLAGNNLKAMEQIN-SCTALQH 128

  Fly   172 LDISNCGLNSFDGTSGLPAIRVLIADGNMIQ--RVDPLAELVHLRVLKARNNRISELGLLSFLGM 234
            ||:|:..::.....|.|.:::.|:..||:|.  |:.|......|.:|....|.|.:|..:|||..
Human   129 LDLSDNNISQIGDLSKLVSLKTLLLHGNIITSLRMAPAYLPRSLAILSLAENEIRDLNEISFLAS 193

  Fly   235 CPQLQEVELQGNP-VCRLPL-----YRSLLARSVPTLQLLDGRVLN 274
            ..:|:::.:..|| |...|.     ||..:......|::|||.|::
Human   194 LTELEQLSIMNNPCVMATPSIPGFDYRPYIVSWCLNLRVLDGYVIS 239

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14185NP_649175.1 LRR_8 144..201 CDD:290566 15/70 (21%)
leucine-rich repeat 146..168 CDD:275380 5/21 (24%)
LRR_4 168..209 CDD:289563 12/42 (29%)
leucine-rich repeat 169..190 CDD:275380 6/20 (30%)
leucine-rich repeat 191..212 CDD:275380 6/22 (27%)
leucine-rich repeat 213..237 CDD:275380 8/23 (35%)
CEP97NP_078824.2 leucine-rich repeat 17..37 CDD:275380 5/19 (26%)
LRR 1 37..58 5/20 (25%)
leucine-rich repeat 38..59 CDD:275380 5/21 (24%)
LRR 2 59..80 5/20 (25%)
leucine-rich repeat 60..81 CDD:275380 4/20 (20%)
LRR_8 63..114 CDD:290566 10/50 (20%)
LRR_RI <78..200 CDD:238064 29/122 (24%)
LRR 3 81..102 3/20 (15%)
leucine-rich repeat 82..103 CDD:275380 3/20 (15%)
LRR_8 103..156 CDD:290566 12/53 (23%)
LRR 4 103..124 5/21 (24%)
leucine-rich repeat 104..125 CDD:275380 5/21 (24%)
LRR_4 124..161 CDD:289563 10/36 (28%)
LRR 5 125..146 5/20 (25%)
leucine-rich repeat 126..147 CDD:275380 6/20 (30%)
LRR_8 147..206 CDD:290566 15/58 (26%)
LRR 6 147..168 6/20 (30%)
leucine-rich repeat 148..171 CDD:275380 6/22 (27%)
LRR 7 171..192 7/20 (35%)
leucine-rich repeat 172..196 CDD:275380 8/23 (35%)
LRR 8 196..205 1/8 (13%)
CCP110-binding 300..750
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 506..529
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 715..769
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.