Protein Alignment CG14185 and Drc3

DIOPT Version :10

• Sequence 1: NP_649175.1
• Gene: CG14185 / 40197
• FlyBaseID: FBgn0036936
• Length: 402
• Species: Drosophila melanogaster
• Sequence 2: NP_083320.1
• Gene: Drc3 / 74665
• MGIID: 1921915
• Length: 523
• Species: Mus musculus
• Alignment Length: 188
• Identity: 49/188 - (26%)
• Similarity: 85/188 - (45%)
• Gaps: 21/188 - (11%)

  Fly    92 LLPVVLPQQGPEPTLDELLRR--------VTQRTDLEAVEQVRLRVISYTVSLSRLSLFLPRLQS 148
            :|...:.:|||:....:|.::        ::.:.|.:.:    ||:       ..|..| ..|:.
Mouse    17 MLKAAVGEQGPQEEAGQLAKQEGILFKDVLSLQLDFQNI----LRI-------DNLWQF-ENLKK 69

  Fly   149 LDLSGSVLSSLRDLGYGLLQLTRLDISNCGLNSFDGTSGLPAIRVLIADGNMIQRVDPLAELVHL 213
            |.|:.:::..:..| ..|:.|..||:|...:.:.:|...|..:..|....|.|.:||.|..||.|
Mouse    70 LQLNNNIIERIEGL-TNLIHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSNNRISKVDSLDALVKL 133

  Fly   214 RVLKARNNRISELGLLSFLGMCPQLQEVELQGNPVCRLPLYRSLLARSVPTLQLLDGR 271
            :||...||:||.:..:.:|...|.|:.:.|.||||.....|:..:...:..|..||.|
Mouse   134 QVLSLGNNQISNMMNIIYLRRFPCLRTLSLAGNPVSEAEEYKMFIYAYLSDLVYLDFR 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14185	NP_649175.1	leucine-rich repeat	146..168	CDD:275380	5/21 (24%)
		PPP1R42	<169..271	CDD:455733	33/101 (33%)
		leucine-rich repeat	169..190	CDD:275380	6/20 (30%)
		leucine-rich repeat	191..212	CDD:275380	7/20 (35%)
		leucine-rich repeat	213..237	CDD:275380	8/23 (35%)
Drc3	NP_083320.1	LRR 1	44..65		5/32 (16%)
		leucine-rich repeat	47..66	CDD:275378	5/30 (17%)
		PPP1R42	53..200	CDD:455733	43/152 (28%)
		LRR 2	66..87		4/21 (19%)
		leucine-rich repeat	67..88	CDD:275378	5/21 (24%)
		LRR 3	88..109		5/20 (25%)
		leucine-rich repeat	89..110	CDD:275378	6/20 (30%)
		LRR 4	110..131		6/20 (30%)
		leucine-rich repeat	111..132	CDD:275378	7/20 (35%)
		LRR 5	132..153		7/20 (35%)
		leucine-rich repeat	133..157	CDD:275378	8/23 (35%)
		leucine-rich repeat	158..169	CDD:275378	5/10 (50%)