DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14185 and Cep97

DIOPT Version :9

Sequence 1:NP_649175.1 Gene:CG14185 / 40197 FlyBaseID:FBgn0036936 Length:402 Species:Drosophila melanogaster
Sequence 2:NP_083091.1 Gene:Cep97 / 74201 MGIID:1921451 Length:856 Species:Mus musculus


Alignment Length:357 Identity:74/357 - (20%)
Similarity:134/357 - (37%) Gaps:79/357 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    97 LPQQGPEPTLDELLRRVTQRTDLEAVEQ-----------VRLRVISYTVSLSRLSL--------- 141
            ||.:....||.....::.:..:||..:|           ||:..::....|..|:|         
Mouse    32 LPCEADVHTLILDKNQIIKLENLEKCKQLIQLSVANNRLVRMMGVAKLTQLRVLNLPHNSIGCVE 96

  Fly   142 ---FLPRLQSLDLSGSVLSSLRDLGYGLLQLTRLDISNCGLNSFDGTSGLPAIRVLIADGNMIQ- 202
               .|..|:.|:|:|:.|.::..:. ....|..||:|:..:......|.|.:::.|:..||:|. 
Mouse    97 GLKDLVHLEWLNLAGNNLKTMEQVN-SCTALQHLDLSDNNIPQIGDVSKLISLKTLLLHGNIITS 160

  Fly   203 -RVDPLAELVHLRVLKARNNRISELGLLSFLGMCPQLQEVELQGNP-VCRLPL-----YRSLLAR 260
             |:.|.....:|.:|....|.|.:|..:|||....:|:::.:..|| |...|.     ||..:..
Mouse   161 LRMAPAYLPRNLSILSLAENEIRDLNEISFLASLSELEQLSIMNNPCVMATPSIPGFDYRPFIVS 225

  Fly   261 SVPTLQLLDGRVLNGEPAPVEMEEATSPASSDLESGSETTAQRPN---------TAPAPEPVPIA 316
            ....|::|||.|::         :..|..:..|.|..:..:.||.         ....|....:.
Mouse   226 WCLNLRVLDGYVIS---------QKESLKAEWLYSQGKGRSYRPGQHIQLVQYLATVCPLTSALG 281

  Fly   317 LNAAIRRQVSASSGSTPVAGSVLSLVRQRRRRSGHAWVSSSSSSGSSSASSARSTRAPSMSSCSS 381
            |..|...::.          .:||..|..:|:     :.|.|.....|..:|..||......|||
Mouse   282 LQTAEDAKLE----------KILSKQRFHQRQ-----LMSQSQDEELSPLAAVETRVHRTPECSS 331

  Fly   382 --------------NSSLDVQSSSHYVFSTQS 399
                          ||.:.:.|:...:::.::
Mouse   332 PGQDFQESEPVLQINSWVGISSNDDQLYAVKN 363

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14185NP_649175.1 LRR_8 144..201 CDD:290566 14/56 (25%)
leucine-rich repeat 146..168 CDD:275380 5/21 (24%)
LRR_4 168..209 CDD:289563 12/42 (29%)
leucine-rich repeat 169..190 CDD:275380 6/20 (30%)
leucine-rich repeat 191..212 CDD:275380 6/22 (27%)
leucine-rich repeat 213..237 CDD:275380 8/23 (35%)
Cep97NP_083091.1 leucine-rich repeat 17..37 CDD:275380 2/4 (50%)
LRR 1 37..58 4/20 (20%)
leucine-rich repeat 38..59 CDD:275380 4/20 (20%)
LRR_4 58..99 CDD:289563 6/40 (15%)
LRR 2 59..80 3/20 (15%)
leucine-rich repeat 60..81 CDD:275380 2/20 (10%)
LRR_8 80..136 CDD:290566 13/56 (23%)
LRR_4 80..122 CDD:289563 9/42 (21%)
LRR 3 81..102 3/20 (15%)
leucine-rich repeat 82..103 CDD:275380 4/20 (20%)
LRR_4 103..144 CDD:289563 9/41 (22%)
LRR 4 103..124 5/21 (24%)
leucine-rich repeat 104..125 CDD:275380 5/21 (24%)
LRR 5 125..146 5/20 (25%)
leucine-rich repeat 126..147 CDD:275380 6/20 (30%)
LRR_8 147..206 CDD:290566 15/58 (26%)
LRR 6 147..168 6/20 (30%)
leucine-rich repeat 148..171 CDD:275380 6/22 (27%)
LRR 7 171..192 7/20 (35%)
leucine-rich repeat 172..196 CDD:275380 8/23 (35%)
LRR 8 196..205 1/8 (13%)
CCP110-binding. /evidence=ECO:0000250 300..742 13/69 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 430..451
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 498..525
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 646..672
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 737..840
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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