DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14185 and lrriq1

DIOPT Version :9

Sequence 1:	NP_649175.1	Gene:	CG14185 / 40197	FlyBaseID:	FBgn0036936	Length:	402	Species:	Drosophila melanogaster
Sequence 2:	XP_009291864.1	Gene:	lrriq1 / 565257	ZFINID:	ZDB-GENE-050419-235	Length:	1511	Species:	Danio rerio

Alignment Length:	343	Identity:	82/343 - (23%)
Similarity:	123/343 - (35%)	Gaps:	126/343 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LAQVRMPPPEVRLNQQNPAQQQQQRMQFNRR-------------QLGRRNSFDRDVAIAEEEQHL 86
            ||.:....|..:|:.||..::|.::.:..:|             :.|..||..:...:..|:  |
Zfish   638 LAWMMSCTPWSKLSLQNKRKEQSKKRKARKRGPSLPPLSEDAILKAGASNSLKQVTTVMLED--L 700

  Fly    87 PAFVHLLPVVLPQQGPEPTLDEL--LRRVTQR----TDLEAVEQV-RLRVISYTVS--------- 135
            |..            ...||.|.  |:.:|.|    |.|:.:.|. ::|.|....:
Zfish   701 PGC------------SLSTLSECNKLQTLTLRRCGLTSLDGLNQCSQIRYIDVQENSITHVDCEG 753

  Fly   136 LSRLSLFL---------------PRLQSLDLSGSVLSSLRDLG------------------YGLL 167
            ||.|.:.|               ..||:|.||.:.:|.:..||                  .||.
Zfish   754 LSSLQILLLGRNQLMNIHGLDEAQNLQTLQLSHNNISLISGLGALKMLLHLSVDHNQLLSTRGLK 818

  Fly   168 Q---LTRLDIS-----------NCG-LNSFD--GTS--GLPA------IRVLIADGNMIQRVD-- 205
            :   |..||.|           ||. ||:.|  |.|  .||.      :|.|..|.|:|..:|
Zfish   819 EIYTLLHLDCSYNYLSHVEGLENCALLNTLDLKGNSLTELPVLQNHVLLRDLYLDDNLIPSLDDL 883

  Fly   206 ----------------------PLAELVHLRVLKARNNRISEL-GLLSFLGMCPQLQEVELQGNP 247
                                  ||.:||.|:.|...:|.:|:| .|...|..|..|||:.|..||
Zfish   884 KSYWLPLLQNLSVVQNSITHLSPLLDLVSLKTLDVSHNCLSDLQDLCLNLQECSSLQELSLTVNP 948

  Fly   248 VCRLPLYRSLLARSVPTL 265
            :.:...:|||:..:||.|
Zfish   949 LLQENNWRSLILETVPGL 966

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14185	NP_649175.1	LRR_8	144..201	CDD:290566	27/99 (27%)
		leucine-rich repeat	146..168	CDD:275380	10/39 (26%)
		LRR_4	168..209	CDD:289563	21/89 (24%)
		leucine-rich repeat	169..190	CDD:275380	12/36 (33%)
		leucine-rich repeat	191..212	CDD:275380	9/44 (20%)
		leucine-rich repeat	213..237	CDD:275380	8/24 (33%)
lrriq1	XP_009291864.1	LRR_RI	713..952	CDD:238064	59/238 (25%)
		LRR_8	713..767	CDD:290566	12/53 (23%)
		leucine-rich repeat	714..735	CDD:275380	6/20 (30%)
		leucine-rich repeat	736..756	CDD:275380	3/19 (16%)
		LRR_8	755..811	CDD:290566	11/55 (20%)
		leucine-rich repeat	757..778	CDD:275380	2/20 (10%)
		leucine-rich repeat	779..800	CDD:275380	8/20 (40%)
		leucine-rich repeat	801..822	CDD:275380	2/20 (10%)
		leucine-rich repeat	823..844	CDD:275380	6/20 (30%)
		leucine-rich repeat	845..866	CDD:275380	7/20 (35%)
		LRR_8	867..921	CDD:290566	12/53 (23%)
		leucine-rich repeat	867..890	CDD:275380	6/22 (27%)
		leucine-rich repeat	891..912	CDD:275380	3/20 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900