DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14185 and lrrcc1

DIOPT Version :9

Sequence 1:	NP_649175.1	Gene:	CG14185 / 40197	FlyBaseID:	FBgn0036936	Length:	402	Species:	Drosophila melanogaster
Sequence 2:	XP_690381.2	Gene:	lrrcc1 / 561887	ZFINID:	ZDB-GENE-041111-207	Length:	997	Species:	Danio rerio

Alignment Length:	341	Identity:	71/341 - (20%)
Similarity:	121/341 - (35%)	Gaps:	119/341 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 ISYTVSLSRLSLFLPRLQSLDLSGSVLSSLRDLGYGLL---QLTRLDISNCGLNSFDGTSGLPAI 191
            :|...|:|.|:|...||..::              ||.   .:..||:|:..:...:|.:.|.::
Zfish    19 VSLNPSISSLNLHCNRLTKIE--------------GLTTAWHIRHLDLSSNHICRIEGLASLSSL 69

  Fly   192 RVLIADGNMIQRVDPLAELVHLRVLKARNNRISEL-GLLSFLGMCPQLQEVELQG---------- 245
            |.|....|:|.:|:.|..|.:|..|....|:|::| |||...|...:|:.::|..
Zfish    70 RTLNLSCNLITKVEGLDGLTNLTRLNLAYNQINDLTGLLYLHGANYKLKYLQLHSNRLDSMNHLL 134

  Fly   246 --------------------NPVCRLPLYRSLLARSVPTLQLLDGRVLNGEPAPVEMEEATSPAS 290
                                ||||::..||.::.:.:..:..|||         |:....|.|.:
Zfish   135 QCMVGLQNLKYITLSKDGAENPVCKMIGYREMVLQCLHQVTTLDG---------VDRMGNTCPLA 190

  Fly   291 SDLESGSETTAQRPNTAPAPEPVP---------IALNAAIRRQVSASSG--STPVAGSVLSLVRQ 344
            .|                :|..||         |:.:.::..:::.|..  :||....||:   |
Zfish   191 ED----------------SPMDVPGLEDFLEFLISSDTSVNGELAKSDAPLTTPRIDEVLT---Q 236

  Fly   345 RRRRSGHAWV------------------------------SSSSSSGSSSASSARSTRAPSMSSC 379
            .|:|.|.|..                              |:|::..|....:.|.|...|.|.|
Zfish   237 FRQRGGKASTENQENEQRIKKLEQQVSHLIQKVPESDRVNSNSTAQPSVMRKAKRDTDQTSESEC 301

  Fly   380 SSNSSLDVQSSSHYVF 395
            .|..  :.|..|..:|
Zfish   302 DSGK--ENQRHSRVLF 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14185	NP_649175.1	LRR_8	144..201	CDD:290566	12/59 (20%)
		leucine-rich repeat	146..168	CDD:275380	3/24 (13%)
		LRR_4	168..209	CDD:289563	11/40 (28%)
		leucine-rich repeat	169..190	CDD:275380	5/20 (25%)
		leucine-rich repeat	191..212	CDD:275380	7/20 (35%)
		leucine-rich repeat	213..237	CDD:275380	9/24 (38%)
lrrcc1	XP_690381.2	LRR_4	23..65	CDD:289563	12/55 (22%)
		leucine-rich repeat	25..46	CDD:275378	7/34 (21%)
		LRR_8	46..101	CDD:290566	15/54 (28%)
		LRR_4	46..87	CDD:289563	11/40 (28%)
		leucine-rich repeat	47..68	CDD:275378	5/20 (25%)
		LRR_4	68..107	CDD:289563	12/38 (32%)
		leucine-rich repeat	69..90	CDD:275378	7/20 (35%)
		LRR_8	89..149	CDD:290566	11/59 (19%)
		LRR_4	89..133	CDD:289563	11/43 (26%)
		leucine-rich repeat	91..116	CDD:275378	9/24 (38%)
		leucine-rich repeat	117..129	CDD:275378	2/11 (18%)
		Rootletin	754..>869	CDD:291694
		DUF342	<817..895	CDD:302792
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810