DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14185 and LRRC49

DIOPT Version :9

Sequence 1:NP_649175.1 Gene:CG14185 / 40197 FlyBaseID:FBgn0036936 Length:402 Species:Drosophila melanogaster
Sequence 2:NP_001185946.1 Gene:LRRC49 / 54839 HGNCID:25965 Length:691 Species:Homo sapiens


Alignment Length:177 Identity:43/177 - (24%)
Similarity:80/177 - (45%) Gaps:12/177 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly   126 RLRVISYTVSLSRLSLFLPRLQSLDLSGSVLSSLRDLGYGLLQLTRLDISNCGLNSFDGTSGLPA 190
            |::.||...:|..|.:       |||.|:.::.:.::.: |.:|..|:::...|:..|..:||.:
Human   172 RIKKISNLENLKSLDV-------LDLHGNQITKIENINH-LCELRVLNLARNFLSHVDNLNGLDS 228

  Fly   191 IRVLIADGNMIQRVDPLAELVHLRVLKARNNRISELGLLSFLGMCPQLQEVELQGNPVCRLPLYR 255
            :..|....|.|..|..:..|..|:.|....|.||....:|.|.....|.::...|||:.:...|:
Human   229 LTELNLRHNQITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYK 293

  Fly   256 SLLARSVPTLQLLDGRVLNGEPAPVEMEEATSPASSDLESGSETTAQ 302
            ..:.:::..|:.||.:.:..|    |...|:..|..:.|...|:..|
Human   294 HTVLQNMMQLRQLDMKRITEE----ERRMASVLAKKEEEKKRESHKQ 336

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
CG14185NP_649175.1 LRR_8 144..201 CDD:290566 13/56 (23%)
leucine-rich repeat 146..168 CDD:275380 5/21 (24%)
LRR_4 168..209 CDD:289563 10/40 (25%)
leucine-rich repeat 169..190 CDD:275380 6/20 (30%)
leucine-rich repeat 191..212 CDD:275380 5/20 (25%)
leucine-rich repeat 213..237 CDD:275380 7/23 (30%)