Protein Alignment CG14185 and Lrrc49

DIOPT Version :10

• Sequence 1: NP_649175.1
• Gene: CG14185 / 40197
• FlyBaseID: FBgn0036936
• Length: 402
• Species: Drosophila melanogaster
• Sequence 2: NP_001423387.1
• Gene: Lrrc49 / 300763
• RGDID: 1309466
• Length: 752
• Species: Rattus norvegicus
• Alignment Length: 378
• Identity: 73/378 - (19%)
• Similarity: 128/378 - (33%)
• Gaps: 126/378 - (33%)

  Fly    86 LPAFVHLLPVVLPQQGPEPTL--DELL---RRVTQRTDLEAVEQVRLRVISYTVSLSRLSLFLPR 145
            :|:|     .:|.:...|.||  |.|.   :::|....::..|.:||....:.        |:.|
  Rat   141 MPSF-----PILQRSSEEKTLYSDRLTLERQKLTVCPIIDGEEHLRLLNFQHN--------FITR 192

  Fly   146 LQSL-----------------DLSG-SVLSSLRDLGYG------------LLQLTRLDISNCGLN 180
            :|::                 ::|| |.|.|||.|..|            |..|..||:....:.
  Rat   193 IQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQIT 257

  Fly   181 SFDGTSGLPAIRVLIADGNMIQRVDPLAELVHLRVLKARNNRIS-----------ELGLLSF--- 231
            ..:..:.|..:|||....|::..||.|..|..|..|..|:|:|:           :...|||
  Rat   258 KIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQITFVRDVDNLPCLQRLFLSFNNI 322

  Fly   232 --------LGMCPQLQEVELQGNPVCRLPLYRSLLARSVPTLQLLDGRVLNGEPAPVEMEEATSP 288
                    |.....|.::...|||:.:...|:..:.:::..|:.||.:.:..|    |...|:..
  Rat   323 TSFESVSCLAESTSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLDMKRITEE----ERRVASVV 383

  Fly   289 ASSDLESGSETTAQRPNTAPAPEPVPIALNAAIRRQVSASSGSTPVAGSVLSLVRQRRRRS---- 349
            |..:.|...|:..|                                     ||:::::|.:
  Rat   384 AKKEEEKKRESHKQ-------------------------------------SLLKEKKRLTINNV 411

  Fly   350 GHAWVSSSSSSGSSSASSARSTRAPSMSSCSSN-----------SSLDVQSSS 391
            ...|......:..:.....:.:.:|...||..:           .|||...||
  Rat   412 ARKWDLQQRVANIAIIQDRKDSESPPQESCQIDGGTISAFPEEAGSLDAGLSS 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14185	NP_649175.1	leucine-rich repeat	146..168	CDD:275380	11/51 (22%)
		PPP1R42	<169..271	CDD:455733	29/123 (24%)
		leucine-rich repeat	169..190	CDD:275380	4/20 (20%)
		leucine-rich repeat	191..212	CDD:275380	8/20 (40%)
		leucine-rich repeat	213..237	CDD:275380	9/45 (20%)
Lrrc49	NP_001423387.1	leucine-rich repeat	160..177	CDD:275380	2/16 (13%)
		leucine-rich repeat	180..201	CDD:275380	5/28 (18%)
		PPP1R42	183..378	CDD:455733	44/206 (21%)
		leucine-rich repeat	202..223	CDD:275380	4/20 (20%)
		leucine-rich repeat	224..245	CDD:275380	5/20 (25%)
		leucine-rich repeat	246..267	CDD:275380	4/20 (20%)
		leucine-rich repeat	268..289	CDD:275380	8/20 (40%)
		leucine-rich repeat	290..311	CDD:275380	5/20 (25%)
		leucine-rich repeat	312..336	CDD:275380	4/23 (17%)