Protein Alignment CG14185 and Lrrc43

DIOPT Version :10

• Sequence 1: NP_649175.1
• Gene: CG14185 / 40197
• FlyBaseID: FBgn0036936
• Length: 402
• Species: Drosophila melanogaster
• Sequence 2: NP_001163867.1
• Gene: Lrrc43 / 288751
• RGDID: 1561461
• Length: 681
• Species: Rattus norvegicus
• Alignment Length: 451
• Identity: 94/451 - (20%)
• Similarity: 153/451 - (33%)
• Gaps: 159/451 - (35%)

  Fly    79 IAEEEQHLPAFVHLLPVVLPQQGPEPTL------DELLRRVTQRTDLEAVEQV------RLRVIS 131
            :..||:.:.|   ||.:|.....|...|      |..||.:..:..|...:..      .|||:.
  Rat    70 VGPEEETVEA---LLGLVRSSHSPWAMLKDSSAEDRFLRELAIQNPLTIKDTFFYSYFRCLRVVD 131

  Fly   132 YTVSL--SRLSLFL---------------------PRLQSLDLSGSVLSS-----------LRDL 162
            ..|||  ..:..||                     |.|:.|:|.|::::|           |:.|
  Rat   132 KGVSLVDKEILKFLKLEELVLSANKIKDIDANNLPPTLKVLELYGNLIASMECLCSPPPPNLQHL 196

  Fly   163 GYG---LL--------------QLTRLDISNCGLNSFD-------GTSGLPAIRVLIADGNMIQR 203
            |.|   ||              .|..||:   |.|...       |.|.|..:|:|:..||
  Rat   197 GLGHNKLLGPLESLYVTSNNWPLLVSLDL---GFNDLTDLQSMILGLSTLKCLRLLVLQGN---- 254

  Fly   204 VDPLAELVHLRVLKARNNRISELGLLSFLGMCPQLQEVELQGNPVCRLPLYRSLLARS---VPTL 265
              |||.:.:.|....  :.::.|.:|..:.:.|. ::.:.:|     |..:..||||.   |.|:
  Rat   255 --PLALVPYYRGFTV--DSLARLCVLDDITVSPS-EKHQFRG-----LNSHGDLLAREAQFVVTI 309

  Fly   266 ----QLLDGRVLNGEPAP---------------VE-------------------MEEATSPASSD 292
                .:||..:|:.||.|               ||                   ::|...|:|..
  Rat   310 GNVRGVLDSSILDPEPGPDGPFISYSYYVTYDFVEDEEKEGITSGMEELHPDSVLDEIDKPSSGM 374

  Fly   293 LESGSETTAQRPNTAPAPEPVPIALNAAIRRQV-----------SASSGSTPVAGSVLSLVRQRR 346
            .|...|...:..:   ..|.:.:..:.|..|.|           |....|..::..::..:.|..
  Rat   375 DEEEEEEEEEEED---RQEVLSVFQSQAHHRPVRQGGRHRFRPESPEVMSRELSEYIVKEMNQMA 436

  Fly   347 RRSGHAWVSSSSSSGSSSASSARSTRAPSMSSCSSNSS-------LDVQ---SSSHYVFST 397
            ..||.:.::....|.:|.:..:    ||...|..|:..       |||:   |....:|||
  Rat   437 EDSGESGITEVDESETSISIHS----APLPQSIDSSEELAKLRPRLDVRLCPSPGTVLFST 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14185	NP_649175.1	leucine-rich repeat	146..168	CDD:275380	11/49 (22%)
		PPP1R42	<169..271	CDD:455733	29/115 (25%)
		leucine-rich repeat	169..190	CDD:275380	8/27 (30%)
		leucine-rich repeat	191..212	CDD:275380	7/20 (35%)
		leucine-rich repeat	213..237	CDD:275380	3/23 (13%)
Lrrc43	NP_001163867.1	leucine-rich repeat	147..168	CDD:275378	0/20 (0%)
		PPP1R42	150..289	CDD:455733	31/150 (21%)
		leucine-rich repeat	169..192	CDD:275378	5/22 (23%)
		leucine-rich repeat	193..219	CDD:275378	6/25 (24%)
		leucine-rich repeat	220..245	CDD:275378	8/27 (30%)