Protein Alignment CG14185 and Lrrc46

DIOPT Version :10

• Sequence 1: NP_649175.1
• Gene: CG14185 / 40197
• FlyBaseID: FBgn0036936
• Length: 402
• Species: Drosophila melanogaster
• Sequence 2: NP_001004201.1
• Gene: Lrrc46 / 287653
• RGDID: 1303311
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 331
• Identity: 73/331 - (22%)
• Similarity: 119/331 - (35%)
• Gaps: 81/331 - (24%)

  Fly   111 RRVTQRTDLEAVEQVRLRVISYTVSLSRLSLFLPRLQSLDLSGSVLSSLRDLGYGLLQLTRLDIS 175
            :..||:|:    |.|.:.    ...:::.:|..|  :..|||..:..:|.|     |:..|||
  Rat     9 KNATQKTE----EGVHIT----EALITKRNLTFP--EDEDLSEKMFHTLDD-----LETVRLD-- 56

  Fly   176 NCGLNSFDGTSGLPAIRVLIADGNMIQRVDPLAELVHLRVLKARNNRIS------ELGLLSFLGM 234
            ..|:........|..|..|....|.|||::.||.:..||.|....|:|.      :|..|.||.:
  Rat    57 GEGITCIGNLERLRNIHSLYLQSNKIQRIENLACITSLRFLSLAGNQIRHVENLLDLQYLQFLDL 121

  Fly   235 CPQLQE-------------VELQGNPVCRLPLYRSLLARSVPTLQLLDGRVL----------NGE 276
            ...|.|             :.|.|||......||.::..::|.|..||.:.:          ...
  Rat   122 SENLIETLKLDELPQSLLILNLCGNPCTNQDGYRKMVIGALPLLLDLDKQPILERWTSDEEDKSS 186

  Fly   277 PAPVEMEEATSPASS------DLESGSETTAQRPNTA------------------PAPEPVPIA- 316
            ....|..|...|..:      |||.......:|...|                  |....||:|
  Rat   187 DEEEEFPELNGPFCAERGFFKDLEQELHQHQERRQQAALTEHLSRMETQPVLTDLPLLPAVPMAG 251

  Fly   317 -LNAAI-----RRQVSASSGSTPVAGSVLSLVRQRRRRSGHAWVSSSSSSGSSSASSARSTRAPS 375
             .:.|:     :.....::.||.:|.|....|.:.::.|    |.:...:.:::||......|||
  Rat   252 DCSPAVTEEPGKEAAPKATSSTQMASSSKKQVPRNQKGS----VQARKGALAATASKTSLAAAPS 312

  Fly   376 MSSCSS 381
            |:..::
  Rat   313 MTKSTN 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14185	NP_649175.1	leucine-rich repeat	146..168	CDD:275380	5/21 (24%)
		PPP1R42	<169..271	CDD:455733	34/120 (28%)
		leucine-rich repeat	169..190	CDD:275380	5/20 (25%)
		leucine-rich repeat	191..212	CDD:275380	8/20 (40%)
		leucine-rich repeat	213..237	CDD:275380	9/29 (31%)
Lrrc46	NP_001004201.1	LRR 1	49..70		6/27 (22%)
		leucine-rich repeat	50..71	CDD:275378	6/22 (27%)
		PPP1R42	60..177	CDD:455733	30/116 (26%)
		LRR 2	71..92		8/20 (40%)
		leucine-rich repeat	72..93	CDD:275378	8/20 (40%)
		LRR 3	93..114		5/20 (25%)
		leucine-rich repeat	94..115	CDD:275378	6/20 (30%)
		LRR 4	115..135		5/19 (26%)
		leucine-rich repeat	116..137	CDD:275378	5/20 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..323		14/71 (20%)