DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14185 and Drc3

DIOPT Version :9

Sequence 1:	NP_649175.1	Gene:	CG14185 / 40197	FlyBaseID:	FBgn0036936	Length:	402	Species:	Drosophila melanogaster
Sequence 2:	NP_001013879.1	Gene:	Drc3 / 287371	RGDID:	1309150	Length:	523	Species:	Rattus norvegicus

Alignment Length:	188	Identity:	49/188 - (26%)
Similarity:	86/188 - (45%)	Gaps:	21/188 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 LLPVVLPQQGPEPTLDELLRR--------VTQRTDLEAVEQVRLRVISYTVSLSRLSLFLPRLQS 148
            :|.|.:.:|||:....:|.::        :..:.|.:.:    ||:       ..|..| ..|:.
  Rat    17 MLKVAVGEQGPQEEAGQLAKQEGILFKDVLALQLDFQNI----LRI-------DNLWQF-ENLRK 69

  Fly   149 LDLSGSVLSSLRDLGYGLLQLTRLDISNCGLNSFDGTSGLPAIRVLIADGNMIQRVDPLAELVHL 213
            |.|:.:::..:..| ..|..|..||:|...:.:.:|...|..:..|....|.|.::|.|..||:|
  Rat    70 LQLNNNIIERIEGL-ENLTHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSHNRISKIDSLDPLVNL 133

  Fly   214 RVLKARNNRISELGLLSFLGMCPQLQEVELQGNPVCRLPLYRSLLARSVPTLQLLDGR 271
            :||...||:|:.:..:.:|...|.|:.:.|.||||.....|:..:...:|.|..||.|
  Rat   134 QVLSLGNNQINNMMNIIYLRRFPCLRTLSLSGNPVSEAEEYKVFIYAYLPDLVYLDFR 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14185	NP_649175.1	LRR_8	144..201	CDD:290566	13/56 (23%)
		leucine-rich repeat	146..168	CDD:275380	5/21 (24%)
		LRR_4	168..209	CDD:289563	11/40 (28%)
		leucine-rich repeat	169..190	CDD:275380	6/20 (30%)
		leucine-rich repeat	191..212	CDD:275380	6/20 (30%)
		leucine-rich repeat	213..237	CDD:275380	7/23 (30%)
Drc3	NP_001013879.1	LRR 1	44..65		5/32 (16%)
		leucine-rich repeat	48..66	CDD:275378	5/29 (17%)
		LRR_4	65..105	CDD:289563	9/40 (23%)
		LRR_8	66..121	CDD:290566	13/55 (24%)
		LRR 2	66..87		4/21 (19%)
		leucine-rich repeat	67..88	CDD:275378	5/21 (24%)
		LRR_4	87..129	CDD:289563	11/41 (27%)
		LRR 3	88..109		5/20 (25%)
		leucine-rich repeat	89..110	CDD:275378	6/20 (30%)
		LRR 4	110..131		5/20 (25%)
		leucine-rich repeat	111..132	CDD:275378	6/20 (30%)
		LRR 5	132..153		6/20 (30%)
		leucine-rich repeat	158..169	CDD:275378	5/10 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810