DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14185 and Lrrcc1

DIOPT Version :9

Sequence 1:	NP_649175.1	Gene:	CG14185 / 40197	FlyBaseID:	FBgn0036936	Length:	402	Species:	Drosophila melanogaster
Sequence 2:	NP_001094115.3	Gene:	Lrrcc1 / 266808	RGDID:	628722	Length:	1025	Species:	Rattus norvegicus

Alignment Length:	184	Identity:	51/184 - (27%)
Similarity:	92/184 - (50%)	Gaps:	35/184 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 SLSRLSLFLPRLQSLDLSGSVLSSLRDLGYGLLQLTRLDISNCGLNSFDGTSGLPAIRVLIADGN 199
            |:|.|||. ..|.:::|..:.:|.:..:.: :..|..||:|:..::..:|.:.|..:..|....|
  Rat    30 SISELSLD-SSLHAINLHCNNISKITSIDH-IWNLRHLDLSSNQISQIEGLNTLTKLCTLNLSCN 92

  Fly   200 MIQRVDPLAELVHLRVLKARNNRISEL-GLLSFLGMCPQLQEVEL-------------------- 243
            :|.||:.|..||:|..|....|.||:| ||:...|:..:|:.::|
  Rat    93 LITRVEGLEALVNLTRLNLSYNHISDLSGLIPLHGLKYKLRYIDLHSNYIDSIHHLLQCTVGLHF 157

  Fly   244 ----------QGNPVCRLPLYRSLLARSVPTLQLLDGRVLNGEPAPVEMEEATS 287
                      :|||:|.:|.||:::.:::|.|::||.:.:.||  ||.:||..|
  Rat   158 LTNLILEKDGEGNPICLVPGYRAIILQTLPQLRILDCKNIFGE--PVSLEEMNS 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14185	NP_649175.1	LRR_8	144..201	CDD:290566	11/56 (20%)
		leucine-rich repeat	146..168	CDD:275380	3/21 (14%)
		LRR_4	168..209	CDD:289563	12/40 (30%)
		leucine-rich repeat	169..190	CDD:275380	6/20 (30%)
		leucine-rich repeat	191..212	CDD:275380	7/20 (35%)
		leucine-rich repeat	213..237	CDD:275380	9/24 (38%)
Lrrcc1	NP_001094115.3	PPP1R42	25..197	CDD:411060	44/168 (26%)
		leucine-rich repeat	40..61	CDD:275378	3/21 (14%)
		leucine-rich repeat	62..83	CDD:275378	6/20 (30%)
		leucine-rich repeat	84..105	CDD:275378	7/20 (35%)
		leucine-rich repeat	106..131	CDD:275378	9/24 (38%)
		leucine-rich repeat	132..145	CDD:275378	2/12 (17%)
		leucine-rich repeat	158..188	CDD:275380	7/29 (24%)
		Smc	426..>758	CDD:224117
		Smc	<639..1020	CDD:224117
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810