Protein Alignment CG14185 and DNAAF11

DIOPT Version :10

• Sequence 1: NP_649175.1
• Gene: CG14185 / 40197
• FlyBaseID: FBgn0036936
• Length: 402
• Species: Drosophila melanogaster
• Sequence 2: XP_006716601.2
• Gene: DNAAF11 / 23639
• HGNCID: 16725
• Length: 472
• Species: Homo sapiens
• Alignment Length: 175
• Identity: 48/175 - (27%)
• Similarity: 72/175 - (41%)
• Gaps: 30/175 - (17%)

  Fly   107 DELLRRVTQRTDLEAVEQVRLRVISYTVSLSRLSLF---LPRLQSLDLSGSVLSSLRDLGYGLLQ 168
            ::|:||..:..|.         ||   .||..|||.   :.||:.:|      ...|||....||
Human    12 EDLIRRNAEHNDC---------VI---FSLEELSLHQQEIERLEHID------KWCRDLKILYLQ 58

  Fly   169 LTRLDISNCGLNSFDGTSGLPAIRVLIADGNMIQRVDPLAELVHLRVLKARNNRISELGLLSFLG 233
                   |..:...:..|.|..:..|....|.|::::.|.....|..|....|.|.||..:..|.
Human    59 -------NNLIGKIENVSKLKKLEYLNLALNNIEKIENLEGCEELAKLDLTVNFIGELSSIKNLQ 116

  Fly   234 MCPQLQEVELQGNPVCRLPLYRSLLARSVPTLQLLDGRVLNGEPA 278
            ....|:|:.|.|||......||..:..::|.|:.|||:.:  ||:
Human   117 HNIHLKELFLMGNPCASFDHYREFVVATLPQLKWLDGKEI--EPS 159

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14185	NP_649175.1	leucine-rich repeat	146..168	CDD:275380	5/21 (24%)
		PPP1R42	<169..271	CDD:455733	26/101 (26%)
		leucine-rich repeat	169..190	CDD:275380	3/20 (15%)
		leucine-rich repeat	191..212	CDD:275380	4/20 (20%)
		leucine-rich repeat	213..237	CDD:275380	7/23 (30%)
DNAAF11	XP_006716601.2	PPP1R42	<29..161	CDD:455733	41/146 (28%)
		leucine-rich repeat	29..51	CDD:275378	7/27 (26%)
		leucine-rich repeat	52..73	CDD:275378	6/27 (22%)
		leucine-rich repeat	74..95	CDD:275378	4/20 (20%)
		leucine-rich repeat	96..120	CDD:275378	7/23 (30%)