Protein Alignment CG14185 and T05H4.3

DIOPT Version :9

• Sequence 1: NP_649175.1
• Gene: CG14185 / 40197
• FlyBaseID: FBgn0036936
• Length: 402
• Species: Drosophila melanogaster
• Sequence 2: NP_001343670.1
• Gene: T05H4.3 / 188149
• WormBaseID: WBGene00020266
• Length: 1150
• Species: Caenorhabditis elegans
• Alignment Length: 372
• Identity: 74/372 - (19%)
• Similarity: 142/372 - (38%)
• Gaps: 109/372 - (29%)

  Fly    72 SFDRDVAIAEEEQHLPAF--------VHLLPVVLPQQGPEPTL---DELLRR-VTQRTDLEAVEQ 124
            |.||.: |..||:|:...        :.|:..:.|:...:..|   |:.:.: :.:::.:|.:.|
 Worm   791 SLDRQI-IPLEERHVNTMKQTTRGLSLELIERICPEWKNKKELMICDQKIEQIILEKSQMEELSQ 854

  Fly   125 VRLRVISYT--VSLSRLSLF--------------------------LPRLQSLDLSGSVLSSLRD 161
            :||..:|..  .|:..:|.|                          .|.|::||:|.:.:|:...
 Worm   855 IRLIDLSKNRLSSVREISSFNITHLILNNNCLKSIAVNDGQTSLQPFPYLENLDISNNSISNTSI 919

  Fly   162 LGYG---LLQLTRLDISNCGLNSFD-GTSGLPAIRVLIADGNMIQRV--DPLAELVHLRV----- 215
            |..|   ||:|..:::|...|:.|| ....||.:..:....|.|:.:  .||..|..|.:
 Worm   920 LRLGIPLLLKLKNINLSQNALSRFDCSLFDLPNLESVDLSNNSIKTIIRRPLKTLTSLNLQNNKL 984

  Fly   216 -------------LKARNNRISELGLLSFLGMCPQLQEVELQGNPVCRLPLYRSLLARSVPTLQL 267
                         |...||:::....|..|..|..|:.::.:.|.|....:|...:...||:::.
 Worm   985 TTLTPLSCPNLVSLDISNNKLASCASLKPLCECKTLENLDCRNNSVTERRVYVDFIKAQVPSVRK 1049

  Fly   268 LDGRVLNGEPAPVEMEEATSPASSDLESGSETTAQ---------------------------RPN 305
            ||..:::.|   :|:.:.....::||.|.|..::.                           .|:
 Worm  1050 LDDEIMSNE---IEITKRRLSRANDLISMSRRSSMVTSSMLSWFEREEGETLENVKRASSFLEPS 1111

  Fly   306 TAPAP------EPVPIALNAAIRRQVSASSGSTPVAGSVLSLVRQRR 346
            .|..|      ||:|      .||:.::.|....:.|:  ..|:.|:
 Worm  1112 AAETPMRPRRLEPLP------GRRKTNSESNGLMLLGT--KAVQHRK 1150

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14185	NP_649175.1	LRR_8	144..201	CDD:290566	18/60 (30%)
		leucine-rich repeat	146..168	CDD:275380	8/24 (33%)
		LRR_4	168..209	CDD:289563	11/43 (26%)
		leucine-rich repeat	169..190	CDD:275380	6/21 (29%)
		leucine-rich repeat	191..212	CDD:275380	5/22 (23%)
		leucine-rich repeat	213..237	CDD:275380	7/41 (17%)
T05H4.3	NP_001343670.1	leucine-rich repeat	69..91	CDD:275380
		leucine-rich repeat	92..113	CDD:275380
		leucine-rich repeat	114..135	CDD:275380
		leucine-rich repeat	136..157	CDD:275380
		leucine-rich repeat	158..181	CDD:275380
		leucine-rich repeat	182..206	CDD:275380
		leucine-rich repeat	629..650	CDD:275380
		PLN00113	645..>1005	CDD:331614	45/214 (21%)
		leucine-rich repeat	651..672	CDD:275380
		leucine-rich repeat	673..692	CDD:275380
		leucine-rich repeat	693..714	CDD:275380
		leucine-rich repeat	715..761	CDD:275380
		leucine-rich repeat	762..815	CDD:275380	7/24 (29%)
		leucine-rich repeat	816..851	CDD:275380	4/34 (12%)
		leucine-rich repeat	855..875	CDD:275380	5/19 (26%)
		leucine-rich repeat	876..903	CDD:275380	0/26 (0%)
		leucine-rich repeat	904..952	CDD:275380	15/47 (32%)
		leucine-rich repeat	953..973	CDD:275380	4/19 (21%)
		leucine-rich repeat	974..994	CDD:275380	2/19 (11%)
		leucine-rich repeat	995..1019	CDD:275380	6/23 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810