Protein Alignment CG14185 and T05H4.3

DIOPT Version :10

• Sequence 1: NP_649175.1
• Gene: CG14185 / 40197
• FlyBaseID: FBgn0036936
• Length: 402
• Species: Drosophila melanogaster
• Sequence 2: NP_001343670.1
• Gene: T05H4.3 / 188149
• WormBaseID: WBGene00020266
• Length: 1150
• Species: Caenorhabditis elegans
• Alignment Length: 372
• Identity: 74/372 - (19%)
• Similarity: 142/372 - (38%)
• Gaps: 109/372 - (29%)

  Fly    72 SFDRDVAIAEEEQHLPAF--------VHLLPVVLPQQGPEPTL---DELLRR-VTQRTDLEAVEQ 124
            |.||.: |..||:|:...        :.|:..:.|:...:..|   |:.:.: :.:::.:|.:.|
 Worm   791 SLDRQI-IPLEERHVNTMKQTTRGLSLELIERICPEWKNKKELMICDQKIEQIILEKSQMEELSQ 854

  Fly   125 VRLRVISYT--VSLSRLSLF--------------------------LPRLQSLDLSGSVLSSLRD 161
            :||..:|..  .|:..:|.|                          .|.|::||:|.:.:|:...
 Worm   855 IRLIDLSKNRLSSVREISSFNITHLILNNNCLKSIAVNDGQTSLQPFPYLENLDISNNSISNTSI 919

  Fly   162 LGYG---LLQLTRLDISNCGLNSFD-GTSGLPAIRVLIADGNMIQRV--DPLAELVHLRV----- 215
            |..|   ||:|..:::|...|:.|| ....||.:..:....|.|:.:  .||..|..|.:
 Worm   920 LRLGIPLLLKLKNINLSQNALSRFDCSLFDLPNLESVDLSNNSIKTIIRRPLKTLTSLNLQNNKL 984

  Fly   216 -------------LKARNNRISELGLLSFLGMCPQLQEVELQGNPVCRLPLYRSLLARSVPTLQL 267
                         |...||:::....|..|..|..|:.::.:.|.|....:|...:...||:::.
 Worm   985 TTLTPLSCPNLVSLDISNNKLASCASLKPLCECKTLENLDCRNNSVTERRVYVDFIKAQVPSVRK 1049

  Fly   268 LDGRVLNGEPAPVEMEEATSPASSDLESGSETTAQ---------------------------RPN 305
            ||..:::.|   :|:.:.....::||.|.|..::.                           .|:
 Worm  1050 LDDEIMSNE---IEITKRRLSRANDLISMSRRSSMVTSSMLSWFEREEGETLENVKRASSFLEPS 1111

  Fly   306 TAPAP------EPVPIALNAAIRRQVSASSGSTPVAGSVLSLVRQRR 346
            .|..|      ||:|      .||:.::.|....:.|:  ..|:.|:
 Worm  1112 AAETPMRPRRLEPLP------GRRKTNSESNGLMLLGT--KAVQHRK 1150

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14185	NP_649175.1	leucine-rich repeat	146..168	CDD:275380	8/24 (33%)
		PPP1R42	<169..271	CDD:455733	27/122 (22%)
		leucine-rich repeat	169..190	CDD:275380	6/21 (29%)
		leucine-rich repeat	191..212	CDD:275380	5/22 (23%)
		leucine-rich repeat	213..237	CDD:275380	7/41 (17%)
T05H4.3	NP_001343670.1	LRR	<62..>213	CDD:443914
		leucine-rich repeat	69..91	CDD:275380
		leucine-rich repeat	92..113	CDD:275380
		leucine-rich repeat	114..135	CDD:275380
		leucine-rich repeat	136..157	CDD:275380
		leucine-rich repeat	158..181	CDD:275380
		leucine-rich repeat	182..206	CDD:275380
		PPP1R42	626..793	CDD:455733	1/1 (100%)
		leucine-rich repeat	629..650	CDD:275380
		leucine-rich repeat	651..672	CDD:275380
		leucine-rich repeat	673..692	CDD:275380
		leucine-rich repeat	693..714	CDD:275380
		leucine-rich repeat	715..761	CDD:275380
		LRR	742..>1032	CDD:443914	51/241 (21%)
		leucine-rich repeat	762..815	CDD:275380	7/24 (29%)
		leucine-rich repeat	816..851	CDD:275380	4/34 (12%)
		leucine-rich repeat	855..875	CDD:275380	5/19 (26%)
		leucine-rich repeat	876..903	CDD:275380	0/26 (0%)
		leucine-rich repeat	904..952	CDD:275380	15/47 (32%)
		leucine-rich repeat	953..973	CDD:275380	4/19 (21%)
		leucine-rich repeat	974..994	CDD:275380	2/19 (11%)
		leucine-rich repeat	995..1019	CDD:275380	6/23 (26%)