Protein Alignment CG14185 and U2A

DIOPT Version :10

• Sequence 1: NP_649175.1
• Gene: CG14185 / 40197
• FlyBaseID: FBgn0036936
• Length: 402
• Species: Drosophila melanogaster
• Sequence 2: XP_308200.4
• Gene: U2A / 1269557
• VectorBaseID: AGAMI1_005548
• Length: 248
• Species: Anopheles gambiae
• Alignment Length: 221
• Identity: 59/221 - (26%)
• Similarity: 93/221 - (42%)
• Gaps: 26/221 - (11%)

  Fly   145 RLQSLDLSGSVLSSLRDLGYGLLQLTRLDISNCGLNSFDGTSGLPAIRVLIADGNMIQRV-DPLA 208
            |.:.|||.|..:..:.::|..|.|...:|.|:..:...||...|..::.|:.:.|.|.|: :.|.
Mosquito    20 RDRELDLRGYKIPQIENMGATLDQYDTIDFSDNDIRKLDGFPRLARLKCLLLNNNRIVRIGENLH 84

  Fly   209 E-LVHLRVLKARNNRISELGLLSFLGMCPQLQEVELQGNPVCRLPLYRSLLARSVPTLQLLDGRV 272
            | |.:|:.:....|.|.|||.|..|...|.|:.:.|..|||.....||..:|...|.|:|||.|.
Mosquito    85 ESLPNLQSIILTGNNIQELGDLEPLTKLPNLETLSLLTNPVSTKQHYREYVAFRFPNLRLLDFRK 149

  Fly   273 LNGEPAP------------------VEMEEATSPASSDLESGSETTAQRPNTAPA-----PEPVP 314
            :..:...                  |...:...||.:..||..|..|.: |.:||     .|.:.
Mosquito   150 IRQKEREAANLLFKSKKGKEMHKEIVRKAKRALPAGALGESSPEKQAVQ-NASPADIQKIKEAIK 213

  Fly   315 IALNAAIRRQVSASSGSTPVAGSVLS 340
            .|.|.....:::....|..:.|.:|:
Mosquito   214 RATNLHEVERLNRMLQSGQITGDILN 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14185	NP_649175.1	leucine-rich repeat	146..168	CDD:275380	6/21 (29%)
		PPP1R42	<169..271	CDD:455733	34/103 (33%)
		leucine-rich repeat	169..190	CDD:275380	5/20 (25%)
		leucine-rich repeat	191..212	CDD:275380	7/22 (32%)
		leucine-rich repeat	213..237	CDD:275380	8/23 (35%)
U2A	XP_308200.4	None