DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14185 and LRRC23

DIOPT Version :10

Sequence 1:NP_649175.1 Gene:CG14185 / 40197 FlyBaseID:FBgn0036936 Length:402 Species:Drosophila melanogaster
Sequence 2:NP_964013.1 Gene:LRRC23 / 10233 HGNCID:19138 Length:343 Species:Homo sapiens


Alignment Length:22 Identity:7/22 - (31%)
Similarity:11/22 - (50%) Gaps:2/22 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    83 IDTDSTLSIFMELVHPSVSIYD 104
            :|....|.:.  ||..|:.||:
Human     6 VDPQRPLPVL--LVSVSLGIYE 25

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14185NP_649175.1 leucine-rich repeat 146..168 CDD:275380
PPP1R42 <169..271 CDD:455733
leucine-rich repeat 169..190 CDD:275380
leucine-rich repeat 191..212 CDD:275380
leucine-rich repeat 213..237 CDD:275380
LRRC23NP_964013.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..47 7/22 (32%)
LRR 1 92..113
PPP1R42 <93..163 CDD:455733
leucine-rich repeat 93..114 CDD:275380
LRR 2 114..134
leucine-rich repeat 115..135 CDD:275380
LRR 3 135..155
leucine-rich repeat 136..156 CDD:275380
PPP1R42 146..304 CDD:455733
LRR 4 156..177
leucine-rich repeat 157..180 CDD:275380
LRR 5 180..200
leucine-rich repeat 181..201 CDD:275380
LRR 6 201..222
leucine-rich repeat 202..223 CDD:275380
Interaction with RSPH9. /evidence=ECO:0000269|PubMed:38091523 208..343
leucine-rich repeat 224..246 CDD:275380
leucine-rich repeat 247..271 CDD:275380
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 318..343
Blue background indicates that the domain is not in the aligned region.

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