DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14185 and drc3

DIOPT Version :9

Sequence 1:	NP_649175.1	Gene:	CG14185 / 40197	FlyBaseID:	FBgn0036936	Length:	402	Species:	Drosophila melanogaster
Sequence 2:	NP_001123832.1	Gene:	drc3 / 100170587	XenbaseID:	XB-GENE-1003585	Length:	522	Species:	Xenopus tropicalis

Alignment Length:	183	Identity:	49/183 - (26%)
Similarity:	83/183 - (45%)	Gaps:	5/183 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 LLPVVLPQQGPEPTLDELLRRVTQRTDLEAVEQVRLRVISYTVSLSRLSLFLPRLQSLDLSGSVL 156
            :|...:.:|||:.....:.:  .:..|.:.|..:||. ....:.:..|..| ..|..|.|..:::
Frog    17 MLRNAVEEQGPKEEAGRIAK--LEGIDFKHVSSLRLD-FKNILKIDNLWQF-HSLTKLQLDNNII 77

  Fly   157 SSLRDLGYGLLQLTRLDISNCGLNSFDGTSGLPAIRVLIADGNMIQRVDPLAELVHLRVLKARNN 221
            ..:..|. .|:.|..||:|...:...:|...|..:..|....|.|..|:.:..|.:|:||...||
Frog    78 EKISGLD-TLVHLVWLDLSFNNIEVIEGLKALTKLEDLSLYNNRISVVENMDTLSNLQVLSLGNN 141

  Fly   222 RISELGLLSFLGMCPQLQEVELQGNPVCRLPLYRSLLARSVPTLQLLDGRVLN 274
            .::.|..|.:|....||:.:.|.|||:.....|:..:|..:|.|..||.|:||
Frog   142 NLTSLENLIYLRKFKQLRTLSLAGNPLSEDDQYKLFIAAHLPNLAYLDFRLLN 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14185	NP_649175.1	LRR_8	144..201	CDD:290566	13/56 (23%)
		leucine-rich repeat	146..168	CDD:275380	5/21 (24%)
		LRR_4	168..209	CDD:289563	10/40 (25%)
		leucine-rich repeat	169..190	CDD:275380	6/20 (30%)
		leucine-rich repeat	191..212	CDD:275380	5/20 (25%)
		leucine-rich repeat	213..237	CDD:275380	8/23 (35%)
drc3	NP_001123832.1	leucine-rich repeat	47..66	CDD:275380	4/20 (20%)
		LRR_RI	<60..211	CDD:238064	41/137 (30%)
		leucine-rich repeat	67..88	CDD:275378	5/21 (24%)
		LRR_8	88..143	CDD:290566	16/54 (30%)
		leucine-rich repeat	89..110	CDD:275378	6/20 (30%)
		LRR_4	109..149	CDD:289563	11/39 (28%)
		leucine-rich repeat	111..132	CDD:275378	5/20 (25%)
		leucine-rich repeat	133..157	CDD:275378	8/23 (35%)
		leucine-rich repeat	158..169	CDD:275378	5/10 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910