Protein Alignment CG14186 and Tmem237

DIOPT Version :10

• Sequence 1: NP_649174.1
• Gene: CG14186 / 40196
• FlyBaseID: FBgn0036935
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_001348342.1
• Gene: Tmem237 / 381259
• MGIID: 2138365
• Length: 427
• Species: Mus musculus
• Alignment Length: 603
• Identity: 99/603 - (16%)
• Similarity: 183/603 - (30%)
• Gaps: 217/603 - (35%)

  Fly   105 PGQEEGEEESPLGAGNTRDSPPPPK--QSDGSRNSSGDAMSLRETL---QQLPATHHHRSR-RTH 163
            |..||.:...|      |..||.|.  |...|...:...|..::.|   ..:|.:|..:.: ||
Mouse     7 PPLEEDQARPP------RALPPVPSAIQVCSSFVENNSRMDQQDDLVGEDDIPLSHPKKKKSRT- 64

  Fly   164 SPADPDASFHRGILGYMDRELKQSSPTPSAPAGTGNGTGNGTSTGASRKQQSLSDPQASPAQRSL 228
                                  :||...::..|......|..:.|:......|.:...:||.
Mouse    65 ----------------------KSSLATASSEGHAEPVVNRRAEGSEPPAAELKEHPEAPAP--- 104

  Fly   229 RSRSSFDKSPRRKRSKSESRRRRERKLIAAGEMEV----RQANETLMRYLKQCSDMHDASLSGEL 289
                                 ||::|:....|:|.    |.::.:|:|              .|.
Mouse   105 ---------------------RRQKKIRPPPELETSLTERPSSPSLLR--------------NEN 134

  Fly   290 EIDQSLEERRV----HRKTKSQRDKRGQLISKLYSAGGISSILKELADDIAPADGE--EIYNPFT 348
            .||....|..|    .||.|..:....|..|:|    |:..      :||...:..  |.::.||
Mouse   135 GIDAEPREEAVIPKPRRKAKKTQPAEPQYASEL----GVED------EDILTDEQSTLEHHSRFT 189

  Fly   349 PVVSPTDDAPAHIDKMFLQTSSGYRPVEHSYYKRSFLGAAVRGSAGISASGGGGGCAGGGGGRLD 413
               :|| .....:.|:|::.|..::..:.|        ..::.:..|..|
Mouse   190 ---APT-GVSQPVGKVFVEKSRRFQAADRS--------ELIKTTENIDVS--------------- 227

  Fly   414 GISAAELGGAGRLFRSSGSHAHGGDRMGGNGSGRGSYGDTRCLLDADFNRNGITSNIQLACVVQR 478
                                                         .|...:..|.::.|:  |.|
Mouse   228 ---------------------------------------------MDVKPSWTTRDVALS--VHR 245

  Fly   479 IWLLISNICHGLLAGLALAHLLFVLSSHPMDWAKVINGMSLAGETVSSTAQPPAASTPSAIDIDS 543
            .:.::....||.|||.|:             |..|:..: |||:.:|:.:.
Mouse   246 AFRMVGLFSHGFLAGCAV-------------WNTVVIYV-LAGDQLSNVSN-------------- 282

  Fly   544 GDRGTESGESSSPSAAASGLALISDYAGFAEIYLNTFYCLAIICLVSVFDRMDICRWSFSNASEL 608
                                 |:..|...|..:.:..|.|..:..||.|||.|..:.|.:..:.|
Mouse   283 ---------------------LLQQYKPLAYPFQSLLYLLLALSTVSAFDRTDFAKISVAIRNFL 326

  Fly   609 ISFRWLIITMIYVATIILAICSDSIDEKLYLFNNNANITLTQQEMLSNSVQSVWSSLSVTRSIAA 673
            ......:.:.:|...:||::......::::|:..:.|.:|...| ....:...|..:::..::..
Mouse   327 ALEPTALASFLYFTALILSLSQQMTSDRIHLYEPSVNGSLWAAE-AEEPILVPWIIVNLVVALLV 390

  Fly   674 ISGWIMIGLTPQEDMLYE 691
            ...|:.:...|..|:..|
Mouse   391 GLSWLFLSYRPGMDLSEE 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14186	NP_649174.1	PRK07764	<17..>173	CDD:236090	16/73 (22%)
		TMEM237	<565..687	CDD:464690	23/121 (19%)
Tmem237	NP_001348342.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..172		44/241 (18%)
		TMEM237	162..404	CDD:464690	57/375 (15%)