Protein Alignment CG14186 and Tmem237

DIOPT Version :10

• Sequence 1: NP_649174.1
• Gene: CG14186 / 40196
• FlyBaseID: FBgn0036935
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_001424591.1
• Gene: Tmem237 / 316412
• RGDID: 1306705
• Length: 413
• Species: Rattus norvegicus
• Alignment Length: 624
• Identity: 101/624 - (16%)
• Similarity: 188/624 - (30%)
• Gaps: 236/624 - (37%)

  Fly    91 TSQQTVVLVNGHAPPGQEEGEEESPLGAGNTRDSPP---PPKQSDGSRNSSGDAMSLRETLQ-QL 151
            ||::||    |..||         .||.....:.||   ||..|               .:| ::
  Rat     2 TSRETV----GEPPP---------LLGTSTYAERPPRALPPVPS---------------AIQDEI 38

  Fly   152 PATHHHRSR-RTHSPADPDASFHRGILGYMDRELKQSSPTPSAPAGTGNGTGNGTSTGASRKQQS 215
            |.:|..:.: ||                       :|:|.|::..|......|..:.|:......
  Rat    39 PLSHPKKKKSRT-----------------------KSTPAPASSEGLAEPVVNRRAEGSEPPAAE 80

  Fly   216 LSDPQASPAQRSLRS-------RSSFDKSPRRKRSKSESRRRRERKLIAAGEMEVRQANETLMRY 273
            |.:...:|.||..:.       .:||.:.|     .|.|..|.|      ..|:|....|.::
  Rat    81 LKEYPEAPVQRKQKKIRPPPELETSFTEKP-----SSPSLLRNE------NGMDVEPREEVVI-- 132

  Fly   274 LKQCSDMHDASLSGELEIDQSLEERRVHRKTKSQRDKRGQLISKLYSAGGISSILKELADDIAPA 338
                                    .:..||.|..:....|..|:|    |:.       |:....
  Rat   133 ------------------------PKPRRKAKKMQPAEPQYASEL----GVE-------DEDVIT 162

  Fly   339 DGEEIYNPFTPVVSPTDDAPAHIDKMFLQTSSGYRPVEHSYYKRSFLGAAVRGSAGISASGGGGG 403
            |.:......:...:|| .....:.|:|::.|..::..:.|        ..::.:..:..|
  Rat   163 DEQSTLEHHSRFTAPT-GVSQPVGKIFVEKSRRFQAADRS--------ELIKTTENVDVS----- 213

  Fly   404 CAGGGGGRLDGISAAELGGAGRLFRSSGSHAHGGDRMGGNGSGRGSYGDTRCLLDADFNRNGITS 468
                                                                   .|...:..|.
  Rat   214 -------------------------------------------------------MDMKPSWTTR 223

  Fly   469 NIQLACVVQRIWLLISNICHGLLAGLALAHLLFVLSSHPMDWAKVINGMSLAGETVSSTAQPPAA 533
            ::.|:  |.|.:.:|....||.|||.|:.:::.:              ..|||:..|:.:.
  Rat   224 DVALS--VHRAFRMIGLFSHGFLAGCAVWNIVVI--------------CVLAGDQFSNVSN---- 268

  Fly   534 STPSAIDIDSGDRGTESGESSSPSAAASGLALISDYAGFAEIYLNTFYCLAIICLVSVFDRMDIC 598
                                           |:..|...|..:.:..|.|..:..||.|||:|..
  Rat   269 -------------------------------LLQQYKPLAYPFQSLLYLLLALSTVSAFDRIDFA 302

  Fly   599 RWSFSNASELISFRWLIITMIYVATIILAICSDSIDEKLYLFNNNANITLTQQEMLSNSVQSVWS 663
            :.|.:..:.|......:.:.:|...:.|::......:::||:..:.|.:|...| :...|...|.
  Rat   303 KTSVAIRNFLALEPTALASFLYFTALTLSLSQQMTSDRIYLYEPSVNGSLWPAE-VEEPVLMPWV 366

  Fly   664 SLSVTRSIAAISGWIMIGLTPQEDMLYEHLV---DLTKY 699
            .:::..::.....|:.:...|..| |.|.|:   |:.:|
  Rat   367 IVNLVVALLVGLAWLFLSYRPGMD-LSEELMFFSDVDEY 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14186	NP_649174.1	PRK07764	<17..>173	CDD:236090	19/86 (22%)
		TMEM237	<565..687	CDD:464690	24/121 (20%)
Tmem237	NP_001424591.1	None