DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sNPF-R and gpr83

DIOPT Version :9

Sequence 1:	NP_001262086.1	Gene:	sNPF-R / 40195	FlyBaseID:	FBgn0036934	Length:	600	Species:	Drosophila melanogaster
Sequence 2:	NP_001072505.1	Gene:	gpr83 / 779960	XenbaseID:	XB-GENE-5817068	Length:	420	Species:	Xenopus tropicalis

Alignment Length:	396	Identity:	125/396 - (31%)
Similarity:	194/396 - (48%)	Gaps:	71/396 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 VQIFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYTFM 126
            |:....|.|:.:.|:.:|||:|||:||::|..||:.|::||.|||::||::.:|..|||.:....
Frog    68 VKALLIVAYSVIIVISLFGNILVCHVVIKNSRMQSATSLFIVNLAVADIMITLLNTPFTLVRFVS 132

  Fly   127 GRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRMKLSTCIGI--IVSIWVIA 189
            ..|.||:.:||:..|.|.||:::|.|||.:||:||:.||::|..|||  ||..||  |:.||.:|
Frog   133 STWVFGKLMCHVSRFVQYCSVHVSVLTLMAIALDRHQVIMHPLKPRM--STVKGIICIIVIWFMA 195

  Fly   190 LLATVPYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTA 254
            ...::|:.:|.|:....:..|       |....:
Frog   196 SGFSLPHAVYQKLEQFFIGNT-------VRMVCL------------------------------- 222

  Fly   255 GSTGPEMPYVRVYCEENWPSEQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARAKPGSK 319
                |..||         |::.:.|.....|..|.:|||..:|||.|..::.||  ..|...|..
Frog   223 ----PSFPY---------PADLFWKYLDLATFVLLYVLPLIVISITYTTVAKKL--WLRNAIGDI 272

  Fly   320 SSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDKSNEWRFYILFFFVAHSIAMS 384
            :..:..|.|.:||.|.:||:.:|.||.:.|.|:|...:.......|:....|..|    |..|||
Frog   273 TMEQYYAHRRKKKMTLKMLMLVVVVFAVCWFPLNCYLVLMSSKVISSNNAIYFAF----HWFAMS 333

  Fly   385 STCYNPFLYAWLNENFRKEFKHVLPCF----NPSNNN-IINITRGYNRSDRNTCGPRLHHGKGDG 444
            |||||||:|.||||:||.|.|.:| |.    :|:.:: :.:::..:..:....|    |..:|..
Frog   334 STCYNPFIYCWLNESFRSELKALL-CVCRRRSPAQSHPLQSVSPQFRHAWTENC----HFKQGSS 393

  Fly   445 GMGGGS 450
            ....||
Frog   394 SQAAGS 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_001262086.1	7tm_4	75..>196	CDD:304433	55/122 (45%)
sNPF-R	NP_001262086.1	7tm_1	80..393	CDD:278431	103/314 (33%)
gpr83	NP_001072505.1	7tmA_GPR83	70..353	CDD:320511	114/341 (33%)
		TM helix 1	71..97	CDD:320511	11/25 (44%)
		TM helix 2	104..129	CDD:320511	12/24 (50%)
		TM helix 3	142..172	CDD:320511	15/29 (52%)
		TM helix 4	183..204	CDD:320511	7/20 (35%)
		TM helix 5	233..262	CDD:320511	10/28 (36%)
		TM helix 6	282..312	CDD:320511	11/29 (38%)
		TM helix 7	321..346	CDD:320511	15/28 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1072979at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X589
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920