Protein Alignment sNPF-R and SSTR1

DIOPT Version :10

• Sequence 1: NP_524176.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001040.1
• Gene: SSTR1 / 6751
• HGNCID: 11330
• Length: 391
• Species: Homo sapiens
• Alignment Length: 411
• Identity: 106/411 - (25%)
• Similarity: 187/411 - (45%)
• Gaps: 76/411 - (18%)

  Fly    11 TTTSSSISTSQLPLVSTTNWSLTSPGTTSAILADVAASDEDRSGGIIHNQFVQIFFYVLYATVFV 75
            |.:|.|.|.|..|...........||..:|...:....:..::|.:...|...|....:|:.|.:
Human     6 TASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCL 70

  Fly    76 LGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYTFMGRWAFGRSLCHLVS 140
            :|:.||.:|.||:||...|:|.|||:|.|||::|.|| :|:|||....|.:..|.||..||.||.
Human    71 VGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELL-MLSVPFLVTSTLLRHWPFGALLCRLVL 134

  Fly   141 FAQGCSIYISTLTLTSIAIDRYFVIIYPFH-PRMKLSTCIGII-VSIWVIALLATVPYGMYMKMT 203
            .....:::.|...||.:::|||..:::|.. .|.:..|...:: :.:||::||..:|..::.:
Human   135 SVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSR-- 197

  Fly   204 NELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTAGSTGPEMPYVRVYC 268
                  |...::..|...:::                                  ||
Human   198 ------TAANSDGTVACNMLM----------------------------------PE-------- 214

  Fly   269 EENWPSEQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARAKPGSKSSRREEADRDRKKR 333
                |::::...|...|..:.|:||...|.:|||.|..|:...| .|.|.:..:|.|      ::
Human   215 ----PAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVA-LKAGWQQRKRSE------RK 268

  Fly   334 TNRMLIAMVAVFGLSWLP---INVVNIFDDFDDKSNEWRFYILFFFVAHSIAMSSTCYNPFLYAW 395
            ...|::.:|.||.:.|:|   :.:||:|.:.||.:......||.:        :::|.||.||.:
Human   269 ITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGY--------ANSCANPILYGF 325

  Fly   396 LNENFRKEFKHVLPCFNPSNN 416
            |::||::.|:.:| |.:..:|
Human   326 LSDNFKRSFQRIL-CLSWMDN 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_524176.1	7tmA_NPYR-like	64..404	CDD:320331	91/344 (26%)
		TM helix 1	65..91	CDD:320331	9/25 (36%)
		TM helix 2	98..123	CDD:320331	14/24 (58%)
		TM helix 3	136..166	CDD:320331	9/29 (31%)
		TM helix 4	177..198	CDD:320331	6/21 (29%)
		TM helix 5	278..307	CDD:320331	10/28 (36%)
		TM helix 6	329..359	CDD:320331	8/32 (25%)
		TM helix 7	372..397	CDD:320331	7/24 (29%)
SSTR1	NP_001040.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		9/43 (21%)
		7tmA_SSTR1	59..334	CDD:320636	91/344 (26%)
		TM helix 1	60..86	CDD:320636	9/25 (36%)
		TM helix 2	93..119	CDD:320636	14/26 (54%)
		TM helix 3	130..160	CDD:320636	9/29 (31%)
		TM helix 4	172..194	CDD:320636	6/21 (29%)
		TM helix 5	220..249	CDD:320636	10/28 (36%)
		TM helix 6	264..294	CDD:320636	8/35 (23%)
		TM helix 7	302..327	CDD:320636	7/32 (22%)