Protein Alignment sNPF-R and Npy2r

DIOPT Version :10

• Sequence 1: NP_524176.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_076458.1
• Gene: Npy2r / 66024
• RGDID: 620475
• Length: 381
• Species: Rattus norvegicus
• Alignment Length: 354
• Identity: 122/354 - (34%)
• Similarity: 175/354 - (49%)
• Gaps: 65/354 - (18%)

  Fly    62 VQIFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYTFM 126
            ||:...:.|.::.:|||.||.||.:||::.::|:||||.||.|||::|:|:..|.:|||..||.|
  Rat    49 VQVVLILAYCSIILLGVVGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLM 113

  Fly   127 GRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRMKLSTCIG--IIVSIWVIA 189
            |.|..|..|||||.:|||.::.:||:|||.||:||:..|:|  |...|:|..|.  ||...|.::
  Rat   114 GEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVY--HLESKISKQISFLIIGLAWGVS 176

  Fly   190 LLATVPYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTA 254
            .|...|..::.:.             :|:|.                 .||
  Rat   177 ALLASPLAIFREY-------------SLIEI-----------------IPD-------------- 197

  Fly   255 GSTGPEMPYVRVYCEENWPSEQ---YRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARAKP 316
                    :..|.|.|.||.|:   |..|:...|..:.:|||..|||..|..|..||  :....|
  Rat   198 --------FEIVACTEKWPGEEKSVYGTVYSLSTLLILYVLPLGIISFSYTRIWSKL--KNHVSP 252

  Fly   317 GSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDKSNEWRFYILFFFVAHSI 381
            |:.|....:    |:.:|.:||:.:|.||.:||||::...:..|.|....:.:.|.|.|.|.|.|
  Rat   253 GAASDHYHQ----RRHKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSHVLDLKEYKLIFTVFHII 313

  Fly   382 AMSSTCYNPFLYAWLNENFRKEFKHVLPC 410
            ||.||..||.||.|:|.|:||.|.....|
  Rat   314 AMCSTFANPLLYGWMNSNYRKAFLSAFRC 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_524176.1	7tmA_NPYR-like	64..404	CDD:320331	118/344 (34%)
		TM helix 1	65..91	CDD:320331	10/25 (40%)
		TM helix 2	98..123	CDD:320331	13/24 (54%)
		TM helix 3	136..166	CDD:320331	16/29 (55%)
		TM helix 4	177..198	CDD:320331	6/22 (27%)
		TM helix 5	278..307	CDD:320331	10/28 (36%)
		TM helix 6	329..359	CDD:320331	11/29 (38%)
		TM helix 7	372..397	CDD:320331	14/24 (58%)
Npy2r	NP_076458.1	7tmA_NPY2R	51..336	CDD:320521	118/344 (34%)
		TM helix 1	52..78	CDD:320521	10/25 (40%)
		TM helix 2	85..110	CDD:320521	13/24 (54%)
		TM helix 3	123..153	CDD:320521	16/29 (55%)
		TM helix 4	164..185	CDD:320521	6/20 (30%)
		TM helix 5	216..245	CDD:320521	10/28 (36%)
		TM helix 6	261..291	CDD:320521	11/33 (33%)
		TM helix 7	304..329	CDD:320521	14/24 (58%)