Protein Alignment sNPF-R and hcrtr2

DIOPT Version :9

• Sequence 1: NP_001262086.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001073337.1
• Gene: hcrtr2 / 561260
• ZFINID: ZDB-GENE-070228-3
• Length: 424
• Species: Danio rerio
• Alignment Length: 418
• Identity: 104/418 - (24%)
• Similarity: 178/418 - (42%)
• Gaps: 107/418 - (25%)

  Fly    60 QFVQIFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYT 124
            ::|.|..|:|   ||::.:.||.|||:.|.:|..|:||||.||.||:.:|||:.:..:|.:.:..
Zfish    54 EWVLIAGYIL---VFLVSLVGNTLVCFAVWKNHHMRTVTNYFIVNLSFADILVTITCLPASLVVD 115

  Fly   125 FMGRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRMKLSTCIGIIVSIWVIA 189
            ....|.||::||.::.:.|..|:.:|.|||:.||.||::.|.:|...:.........||.||:::
Zfish   116 ITETWFFGQTLCKILPYLQTISVSVSVLTLSCIAQDRWYAICHPLKFKSTAKRARKSIVLIWLVS 180

  Fly   190 LLATVPYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTA 254
            .:..:|..:.|:                 .::||               |:.|:.|..:
Zfish   181 CIMMIPQAVVME-----------------SSSLM---------------PELTNKTSLF------ 207

  Fly   255 GSTGPEMPYVRVYCEENWPSEQYRKVFGAITTTLQFVLPFFIISICYV----------------- 302
                       ..|:|.||.|.|.||:......:.:..|..::.:.|:
Zfish   208 -----------TVCDEQWPDEIYPKVYHTCFFIVTYFAPLCLMVLAYIQICHKLWCQQIPGSSSV 261

  Fly   303 ----WISVKLNQRARAKPGSKSSRREEADRDRK-----KRTNRMLIAMVAVFGLSWLPINVVNI- 357
                |.|::.:..|.....|...|......:.|     ::|.|||:.::.||.|.:|||:::||
Zfish   262 LQRQWKSLQCSAHAVGSGESVKVRTSTVSAEAKQVKARRKTARMLMVVLFVFALCYLPISILNIM 326

  Fly   358 ---FDDFDDKSNEWRFYILFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHVLPC--------- 410
               |..|.:..|....|..|.| :|.:..:::..||.:|.:|:..||:|||....|
Zfish   327 KRVFGAFKNTGNRETVYAWFTF-SHWLIYANSAANPIIYNFLSGKFREEFKAAFICQCSGRGETH 390

  Fly   411 ---------------FNPSNNNIINITR 423
                           .:...||:.||:|
Zfish   391 KQRARGRTSTDSRKSLSTQVNNLDNISR 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_001262086.1	7tm_4	75..>196	CDD:304433	41/120 (34%)
		7tm_1	80..393	CDD:278431	85/342 (25%)
hcrtr2	NP_001073337.1	7tm_4	65..>185	CDD:304433	42/119 (35%)
		7tm_1	71..364	CDD:278431	85/342 (25%)
		Orexin_rec2	390..>424	CDD:281778	5/29 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3808
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940