Protein Alignment sNPF-R and Qrfprl

DIOPT Version :10

• Sequence 1: NP_524176.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001102709.1
• Gene: Qrfprl / 500157
• RGDID: 1560028
• Length: 415
• Species: Rattus norvegicus
• Alignment Length: 493
• Identity: 115/493 - (23%)
• Similarity: 195/493 - (39%)
• Gaps: 168/493 - (34%)

  Fly    29 NWSLTSPGTTSAILADVAASDEDRSGGIIHN----QFV------------------QIFFYVLYA 71
            :|:||:. ..||:|.             :||    ||:                  ::...:...
  Rat     2 SWNLTAE-QLSALLQ-------------LHNLTRAQFIARYGLRPLVLTPQLPARARLALLLAGL 52

  Fly    72 TVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYTFMGRWAFGRSLC 136
            .:|.|.:|||.||.|||.|::||:|||||||.:|||||:|:....:|.|.|......|..|..:|
  Rat    53 LIFALALFGNALVVYVVTRSKAMRTVTNIFICSLALSDLLIVFFCIPVTMLQNVSDTWLGGAFIC 117

  Fly   137 HLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPF-----HPRMKLSTCIGIIVSIWVIALLATVPY 196
            .:|.|.|..::....||:|.||::|:..:::||     :...:..|.:|:   :|::|::...|.
  Rat   118 KMVPFVQCTAVVTEILTMTCIAVERHQGLVHPFKMKQQYTNQRAFTMLGV---VWLVAIIIGSPM 179

  Fly   197 GMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTAGSTGPEM 261
            ....::                                                         |:
  Rat   180 WHVQRL---------------------------------------------------------EI 187

  Fly   262 PYVRVY------CEENWPSEQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARAKPGS-- 318
            .|..:|      |.|.|.|..::|::........|:||..::|:.|..|..:|..:.|...||
  Rat   188 KYDFLYEKEHICCLEEWSSPVHQKIYTTFILVTLFLLPLLLLSVLYGKIGYELWIKKRVGDGSVL 252

  Fly   319 ---------KSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNI---FDDFDDKSNEWRFY 371
                     |.:|       :|||...|::.:|.:|.:.|.|.:||::   :.:|:.:.:|....
  Rat   253 RTIHGKEMFKIAR-------KKKRAVIMMVTVVVLFAVCWAPFHVVHMMIEYSNFEKEYDEVTIK 310

  Fly   372 ILFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHVLPCFNPSNNNIINITRGYNRSDRNTCGPR 436
            ::|..|......:|.| ||.:||.:||||:|.|...: |:     .:|          :.|..|.
  Rat   311 MIFAIVQIIGFFNSIC-NPIVYALMNENFKKNFVSAV-CY-----CVI----------KETPSPA 358

  Fly   437 LHHG----------------------KGDGGMGGGSLD 452
            ..||                      ||: ..||.::|
  Rat   359 QRHGSLGAIVMHRRVKLAVGENPVEIKGE-AFGGSNMD 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_524176.1	7tmA_NPYR-like	64..404	CDD:320331	93/364 (26%)
		TM helix 1	65..91	CDD:320331	10/25 (40%)
		TM helix 2	98..123	CDD:320331	13/24 (54%)
		TM helix 3	136..166	CDD:320331	10/29 (34%)
		TM helix 4	177..198	CDD:320331	5/20 (25%)
		TM helix 5	278..307	CDD:320331	7/28 (25%)
		TM helix 6	329..359	CDD:320331	10/32 (31%)
		TM helix 7	372..397	CDD:320331	8/24 (33%)
Qrfprl	NP_001102709.1	7tmA_QRFPR	60..342	CDD:320333	91/349 (26%)
		TM helix 2	79..105	CDD:320333	14/25 (56%)
		TM helix 3	117..147	CDD:320333	10/29 (34%)
		TM helix 4	160..181	CDD:320333	5/23 (22%)
		TM helix 5	210..235	CDD:320333	6/24 (25%)
		TM helix 6	265..295	CDD:320333	11/36 (31%)
		TM helix 7	310..335	CDD:320333	8/25 (32%)