DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sNPF-R and NPFR

DIOPT Version :9

Sequence 1:	NP_001262086.1	Gene:	sNPF-R / 40195	FlyBaseID:	FBgn0036934	Length:	600	Species:	Drosophila melanogaster
Sequence 2:	NP_001246947.1	Gene:	NPFR / 40754	FlyBaseID:	FBgn0037408	Length:	489	Species:	Drosophila melanogaster

Alignment Length:	492	Identity:	149/492 - (30%)
Similarity:	225/492 - (45%)	Gaps:	92/492 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 GTTSAI-LADVAASDEDRSGG----------IIHNQFVQIFFY----VLYATVFVLGVFGNVLVC 85
            ||..|: ...:..||.:.:|.          .:.|:.|...:|    .:|..:.|.|..||.||.
  Fly    44 GTVHALNTTAINTSDLNETGSRPLDPVLIDRFLSNRAVDSPWYHMLISMYGVLIVFGALGNTLVV 108

  Fly    86 YVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYTFMGRWAFGRS--LCHLVSFAQGCSIY 148
            ..|:|...|:|..|:||.|||:||:|||::.:|.|.:......|.:|..  ||..::..|...|:
  Fly   109 IAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILCKTIAMLQALCIF 173

  Fly   149 ISTLTLTSIAIDRYFVIIYPFHPRMKLSTCIGIIVSIWVIALLATVPYGMYMKMTNELVNGTQTG 213
            :||:::|:||.|||.||:||....::....:.|:..||.:|||...|..:|    .||:|
  Fly   174 VSTISITAIAFDRYQVIVYPTRDSLQFVGAVTILAGIWALALLLASPLFVY----KELIN----- 229

  Fly   214 NETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTAGSTGPEMPYVRVYCEENWPSEQYR 278
                                         :.|.|.:|.:....|.|       ||.|:|||...|
  Fly   230 -----------------------------TDTPALLQQIGLQDTIP-------YCIEDWPSRNGR 258

  Fly   279 KVFGAITTTLQFVLPFFIISICYVWISVKLNQRARAKPGSKSSRREEADRDRK-KRTNRMLIAMV 342
            ..:...:..:|:::|..|:|:.|..|..||..|........||.:.:.:|.|: ||||.:||::.
  Fly   259 FYYSIFSLCVQYLVPILIVSVAYFGIYNKLKSRITVVAVQASSAQRKVERGRRMKRTNCLLISIA 323

  Fly   343 AVFGLSWLPINVVNIFDDFDDKSNEWRFYILFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHV 407
            .:||:||||:|..|::.|. ::|...:..::.:.:.|.|.|||.|.||.||.|||:||||||:.:
  Fly   324 IIFGVSWLPLNFFNLYADM-ERSPVTQSMLVRYAICHMIGMSSACSNPLLYGWLNDNFRKEFQEL 387

  Fly   408 LPCFNPSNNNIINITRGYN----RSDRNTCGPRLHHGK----GDGGM------GGGSLDADD--- 455
            |...:.:|..:...|.|.|    ...|...|..|..|:    |.||.      |.|.|.|.|
  Fly   388 LCRCSDTNVALNGHTTGCNVQAAARRRRKLGAELSKGELKLLGPGGAQSGTAGGEGGLAATDFMT 452

  Fly   456 -QDENG----ITQETCL------PKEKLLIIPREPTY 481
             ..|.|    ||:...|      |.|...::||...|
  Fly   453 GHHEGGLRSAITESVALTDHNPVPSEVTKLMPRLEQY 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_001262086.1	7tm_4	75..>196	CDD:304433	47/122 (39%)
sNPF-R	NP_001262086.1	7tm_1	80..393	CDD:278431	99/315 (31%)
NPFR	NP_001246947.1	7tm_4	98..>195	CDD:304433	41/96 (43%)
NPFR	NP_001246947.1	7tm_1	103..373	CDD:278431	99/315 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D25205at7147
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41034
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.020